trans-2-Methyl-4-propyl-1,3-oxathiane
INCI: 2-METHYL-4-PROPYL-1,3-OXATHIANE
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
2 study endpoints found for trans-2-Methyl-4-propyl-1,3-oxathiane. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 0.44 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
| dose_tested | 0.44 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
Expert Verdict
Cramer Class III classification demands stricter safety thresholds than the hexenyl esters. Sulfur-containing heterocycle. Limited repeat-dose toxicity data — safety relies on TTC approach rather than substance-specific NOAEL
Regulatory Flags
Frequently Asked Questions
Is trans-2-Methyl-4-propyl-1,3-oxathiane safe in cosmetics?
Cramer Class III classification demands stricter safety thresholds than the hexenyl esters. Sulfur-containing heterocycle. Limited repeat-dose toxicity data — safety relies on TTC approach rather than substance-specific NOAEL The EU classifies trans-2-Methyl-4-propyl-1,3-oxathiane as "permitted". Safety rating: GOOD. 2 toxicological study endpoint(s) are available in our database.
Is trans-2-Methyl-4-propyl-1,3-oxathiane allowed in the EU?
trans-2-Methyl-4-propyl-1,3-oxathiane EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does trans-2-Methyl-4-propyl-1,3-oxathiane do in cosmetics?
trans-2-Methyl-4-propyl-1,3-oxathiane functions as: Perfuming / Fragrance ingredient (tropical, sulfurous, passion fruit note). It is classified as a cosmetic ingredient in our database. CAS number: 67715-80-4.
What is the Margin of Safety for trans-2-Methyl-4-propyl-1,3-oxathiane?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for trans-2-Methyl-4-propyl-1,3-oxathiane?
The NOAEL (No Observed Adverse Effect Level) for trans-2-Methyl-4-propyl-1,3-oxathiane is 0.44 mg/kg bw/day based on a Subchronic study via oral route in rat. A total of 2 study endpoints are available. Source: COSMOS_DB.
Compliance Tools
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