Good Cosmetic Ingredient NOAEL Data

Amylvinyl Carbinol

INCI: AMYLVINYL CARBINOL

CAS Number
3391-86-4
Function
Fragrance, masking agent, perfuming
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes FEMA GRAS 2805; not restricted by FDA in cosmetics

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

2 study endpoints found for Amylvinyl Carbinol. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 14.55 mg/kg bw/day oral rat Subchronic COSMOS_DB
dose_tested 14.55 mg/kg bw/day oral rat Subchronic COSMOS_DB

Expert Verdict

Permitted in cosmetics with adequate safety margin. Classified as harmful to aquatic organisms and readily biodegradable; consider environmental impact in formulations.

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Concern Level: Moderate

Regulatory Flags

fragrance-component ifra_fragrance fda_food_additive

Frequently Asked Questions

Is Amylvinyl Carbinol safe in cosmetics?

Permitted in cosmetics with adequate safety margin. Classified as harmful to aquatic organisms and readily biodegradable; consider environmental impact in formulations. The EU classifies Amylvinyl Carbinol as "permitted". Safety rating: GOOD. 2 toxicological study endpoint(s) are available in our database.

Is Amylvinyl Carbinol allowed in the EU?

Amylvinyl Carbinol EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Amylvinyl Carbinol do in cosmetics?

Amylvinyl Carbinol functions as: Fragrance, masking agent, perfuming. It is classified as a cosmetic ingredient in our database. CAS number: 3391-86-4.

What is the Margin of Safety for Amylvinyl Carbinol?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Amylvinyl Carbinol?

The NOAEL (No Observed Adverse Effect Level) for Amylvinyl Carbinol is 14.55 mg/kg bw/day based on a Subchronic study via oral route in rat. A total of 2 study endpoints are available. Source: COSMOS_DB.

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