trans-2-tert-Butylcyclohexanol

INCI: 2-TERT-BUTYLCYCLOHEXANOL (VERDOL)

CAS Number
5448-22-6 (trans isomer); parent mixed CAS: 13491-79-7
Function
Fragrance ingredient (camphoraceous, piney, minty, tarry aroma)
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted in cosmetics as fragrance ingredient

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Not genotoxic; not phototoxic; Cramer Class I. Screening-level PEC/PNEC was >1 but refined assessment <1

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Concern Level: Moderate

Regulatory Flags

fragrance-component

Frequently Asked Questions

Is trans-2-tert-Butylcyclohexanol safe in cosmetics?

Not genotoxic; not phototoxic; Cramer Class I. Screening-level PEC/PNEC was >1 but refined assessment <1 The EU classifies trans-2-tert-Butylcyclohexanol as "permitted". Safety rating: GOOD.

Is trans-2-tert-Butylcyclohexanol allowed in the EU?

trans-2-tert-Butylcyclohexanol EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does trans-2-tert-Butylcyclohexanol do in cosmetics?

trans-2-tert-Butylcyclohexanol functions as: Fragrance ingredient (camphoraceous, piney, minty, tarry aroma). It is classified as a cosmetic ingredient in our database. CAS number: 5448-22-6 (trans isomer); parent mixed CAS: 13491-79-7.

What is the Margin of Safety for trans-2-tert-Butylcyclohexanol?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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