Trideceth-2

INCI: TRIDECETH-2

CAS Number
24938-91-8 (generic trideceth series)
Function
Emulsifying, surfactant (cleansing), skin conditioning
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes CIR-reviewed — safe as used when formulated to be nonirritating

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Critical: Low-EO alkyl PEG ethers are significantly more irritating and more readily absorbed. Laureth-4 dermal LD₅₀ in rabbits was only 0.93–1.78 mL/kg. Higher penetration enhancement potential. Residual ethylene oxide/1,4-dioxane still applies. Must be formulated to be nonirritating — this is harder to achieve with low-EO ethoxylates

⚠️
Concern Level: Moderate

Frequently Asked Questions

Is Trideceth-2 safe in cosmetics?

Critical: Low-EO alkyl PEG ethers are significantly more irritating and more readily absorbed. Laureth-4 dermal LD₅₀ in rabbits was only 0.93–1.78 mL/kg. Higher penetration enhancement potential. Residual ethylene oxide/1,4-dioxane still applies. Must be formulated to be nonirritating — this is harder to achieve with low-EO ethoxylates The EU classifies Trideceth-2 as "permitted". Safety rating: MODERATE.

Is Trideceth-2 allowed in the EU?

Trideceth-2 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Trideceth-2 do in cosmetics?

Trideceth-2 functions as: Emulsifying, surfactant (cleansing), skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 24938-91-8 (generic trideceth series).

What is the Margin of Safety for Trideceth-2?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

📱

Is Trideceth-2 in Your Products?

Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free →

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Trideceth-2 in your formulation.