Trifluoroacetyl Tripeptide-2

INCI: TRIFLUOROACETYL TRIPEPTIDE-2

CAS Number
64577-63-5
Function
Skin Conditioning, Skin Protecting (anti-aging peptide, marketed as "Progeline")
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted in cosmetics; no specific restrictions

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Trifluoroacetic acid (TFA) moiety is persistent in the environment; incorporate at final manufacturing stage, pH 5โ€“7 optimal; insoluble in water

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Concern Level: Low

Frequently Asked Questions

Is Trifluoroacetyl Tripeptide-2 safe in cosmetics?

Trifluoroacetic acid (TFA) moiety is persistent in the environment; incorporate at final manufacturing stage, pH 5โ€“7 optimal; insoluble in water The EU classifies Trifluoroacetyl Tripeptide-2 as "permitted". Safety rating: GOOD.

Is Trifluoroacetyl Tripeptide-2 allowed in the EU?

Trifluoroacetyl Tripeptide-2 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Trifluoroacetyl Tripeptide-2 do in cosmetics?

Trifluoroacetyl Tripeptide-2 functions as: Skin Conditioning, Skin Protecting (anti-aging peptide, marketed as "Progeline"). It is classified as a cosmetic ingredient in our database. CAS number: 64577-63-5.

What is the Margin of Safety for Trifluoroacetyl Tripeptide-2?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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