Progeline (Trifluoroacetyl Tripeptide-2) — Structu

INCI: TRIFLUOROACETYL TRIPEPTIDE-2

CAS Number
64577-63-5
Function
skin conditioning and skin protecting agent
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
EU Max Conc. 10%
🇺🇸 US Status permitted
US Notes CIR (Cosmetic Ingredient Review) has not published a safety assessment for Trifluoroacetyl Tripeptide-2

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Insufficient safety data available for Trifluoroacetyl Tripeptide-2. CIR has not completed a safety assessment; further evaluation recommended before widespread use.

⚠️
Concern Level: Moderate

Frequently Asked Questions

Is Progeline (Trifluoroacetyl Tripeptide-2) — Structu safe in cosmetics?

Insufficient safety data available for Trifluoroacetyl Tripeptide-2. CIR has not completed a safety assessment; further evaluation recommended before widespread use. The EU classifies Progeline (Trifluoroacetyl Tripeptide-2) — Structu as "permitted". Safety rating: MODERATE.

Is Progeline (Trifluoroacetyl Tripeptide-2) — Structu allowed in the EU?

Progeline (Trifluoroacetyl Tripeptide-2) — Structu EU regulatory status: permitted. Maximum allowed concentration: 10%. This is based on EU Regulation 1223/2009 and its amendments.

What does Progeline (Trifluoroacetyl Tripeptide-2) — Structu do in cosmetics?

Progeline (Trifluoroacetyl Tripeptide-2) — Structu functions as: skin conditioning and skin protecting agent. It is classified as a Active Ingredient in our database. CAS number: 64577-63-5.

What is the Margin of Safety for Progeline (Trifluoroacetyl Tripeptide-2) — Structu?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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