NOAEL Studies
Cosmetic Ingredient
Triheptanoin NOAEL Studies
INCI: TRIHEPTANOIN
CAS: 620-67-7
Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.
CIR Safety Assessment 6 endpoints
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| CIR Safety Assessment | NOAEL | =3.5 | g/kg/day | rat | oral | 30 days | oral toxicity | 38; 10; 30, p.33 |
| CIR Safety Assessment | NOAEL | =5 | % | rat | oral | SUBCHRONIC | repeated dose toxicity | (7; 3; 42, p.34 |
| CIR Safety Assessment | NOAEL | =10 | mg/kg bw/d | rat | oral | 30 d | repeated dose toxicity | 36; 37; 0, p.30 |
| CIR Safety Assessment | NOAEL | =10 | g/kg | rat | oral | chronic | oral toxicity | 3; 6; 38, p.33 |
| CIR Safety Assessment | NOAEL | =15 | % | rat | oral | 91 days | oral toxicity | 5; 39; 4, p.34 |
| CIR Safety Assessment | NOAEL | =3500 | mg/kg/d | rat | oral | 30 d | repeated dose toxicity | 37; 0; 5, p.30 |
Regulatory source 6 endpoints
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| Regulatory source | oral toxicity | 3.5 | g/kg/day | rat | oral | 30 days | oral toxicity | p.33 |
| Regulatory source | oral toxicity | 10 | g/kg | rat | oral | chronic | oral toxicity | p.33 |
| Regulatory source | oral toxicity | 15 | % | rat | oral | 91 days | oral toxicity | p.34 |
| Regulatory source | repeated dose toxicity | 5 | % | rat | oral | SUBCHRONIC | repeated dose toxicity | p.34 |
| Regulatory source | repeated dose toxicity | 10 | mg/kg bw/d | rat | oral | 30 d | repeated dose toxicity | p.30 |
| Regulatory source | repeated dose toxicity | 3500 | mg/kg/d | rat | oral | 30 d | repeated dose toxicity | p.30 |
openFDA substances 1 endpoint
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| openFDA substances | FDA UNII substance identifier | 2P6O7CFW5K | UNII | - | - | - | chemical | - |