Tripeptide-38

INCI: TRIPEPTIDE-38

CAS Number
1447824-23-8 (Palmitoyl Tripeptide-38, trade name Matrixyl Synthe'6)
Function
3D skin remodeling; filler effect; anti-aging (collagen/ECM stimulation)
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No specific restriction; widely used in US market anti-aging products

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Most robust dataset in this group; CIR reviewed palmitoyl oligopeptides as a class

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Concern Level: Low

Frequently Asked Questions

Is Tripeptide-38 safe in cosmetics?

Most robust dataset in this group; CIR reviewed palmitoyl oligopeptides as a class The EU classifies Tripeptide-38 as "permitted". Safety rating: GOOD.

Is Tripeptide-38 allowed in the EU?

Tripeptide-38 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Tripeptide-38 do in cosmetics?

Tripeptide-38 functions as: 3D skin remodeling; filler effect; anti-aging (collagen/ECM stimulation). It is classified as a cosmetic ingredient in our database. CAS number: 1447824-23-8 (Palmitoyl Tripeptide-38, trade name Matrixyl Synthe'6).

What is the Margin of Safety for Tripeptide-38?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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