Regulatory Status
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Safety Data
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SCCS NOAEL Values
NOAEL/LOAEL values cited in official SCCS opinions for Triphenyl Phosphate.
| NOAEL | LOAEL | Route | Species | Study | DA% (SCCS) | Opinion |
|---|---|---|---|---|---|---|
| 100 mg/kg/day | 300 mg/kg/day | Oral | Rat | Subchronic (90-day) (90 days (dietary)) | 100 | SCCS/1664/24 (2024) |
Expert Verdict
🔴 CRITICAL: Potential endocrine disruptor — SCCS opinion explicitly raised concerns. Also used as fire retardant (non-cosmetic), raising bioaccumulation questions. Monitor EU regulatory developments closely — potential Annex II/III listing pending. OECD classifies as low hazard but this predates ED screening data. Avoid use near cuticles/broken skin.
Regulatory Flags
Frequently Asked Questions
Is Triphenyl Phosphate safe in cosmetics?
🔴 CRITICAL: Potential endocrine disruptor — SCCS opinion explicitly raised concerns. Also used as fire retardant (non-cosmetic), raising bioaccumulation questions. Monitor EU regulatory developments closely — potential Annex II/III listing pending. OECD classifies as low hazard but this predates ED screening data. Avoid use near cuticles/broken skin. The EU classifies Triphenyl Phosphate as "permitted". Safety rating: MODERATE.
Is Triphenyl Phosphate allowed in the EU?
Triphenyl Phosphate EU regulatory status: permitted. Maximum allowed concentration: 5%. This is based on EU Regulation 1223/2009 and its amendments.
What does Triphenyl Phosphate do in cosmetics?
Triphenyl Phosphate functions as: Plasticizer (primarily in nail products); also fire retardant. It is classified as a cosmetic ingredient in our database. CAS number: 115-86-6 (EC No. 204-112-2).
What is the Margin of Safety for Triphenyl Phosphate?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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