Moderate Cosmetic Ingredient

Hyaluronate rh-Oligopeptide-1

INCI: HYALURONATE RH-OLIGOPEPTIDE-1

CAS Number
Not assigned (biotech conjugate)
Function
Skin protecting
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted — no CFR restriction for cosmetic use

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Very limited independent toxicological data; biotech origin requires verified absence of host-cell proteins and endotoxins; recombinant peptide moiety may raise regulatory questions in certain ASEAN markets. No CIR or SCCS opinion exists.

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Concern Level: Moderate

Frequently Asked Questions

Is Hyaluronate rh-Oligopeptide-1 safe in cosmetics?

Very limited independent toxicological data; biotech origin requires verified absence of host-cell proteins and endotoxins; recombinant peptide moiety may raise regulatory questions in certain ASEAN markets. No CIR or SCCS opinion exists. The EU classifies Hyaluronate rh-Oligopeptide-1 as "permitted". Safety rating: MODERATE.

Is Hyaluronate rh-Oligopeptide-1 allowed in the EU?

Hyaluronate rh-Oligopeptide-1 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Hyaluronate rh-Oligopeptide-1 do in cosmetics?

Hyaluronate rh-Oligopeptide-1 functions as: Skin protecting. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned (biotech conjugate).

What is the Margin of Safety for Hyaluronate rh-Oligopeptide-1?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check Hyaluronate rh-Oligopeptide-1 compliance across multiple jurisdictions:

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Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
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Substance Compliance
Check compliance across 55 jurisdictions
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
Compare limits across jurisdictions

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