Tripropylene Glycol Acrylate

INCI: TRIPROPYLENE GLYCOL DIACRYLATE (TPGDA)

CAS Number
42978-66-5 (Tripropylene Glycol Diacrylate — the most common commercial form)
Function
UV-curable reactive diluent/crosslinker — primarily industrial use in radiation-curing coatings, inks, adhesives
Safety Rating
POOR

Regulatory Status

🇪🇺 EU Status restricted
🇺🇸 US Status restricted
US Notes Not specifically listed for cosmetic use; certain acrylate monomers are restricted

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

CRITICAL: Reactive acrylate monomer — not suitable for leave-on or rinse-off cosmetic formulations. GHS hazards: H315, H317 (skin sensitizer Cat 1), H319. If encountered in a cosmetic context, likely refers to a fully cured/polymerized acrylate system, not the free monomer. Verify polymerization state and residual monomer levels

⚠️
Concern Level: High

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is Tripropylene Glycol Acrylate safe in cosmetics?

CRITICAL: Reactive acrylate monomer — not suitable for leave-on or rinse-off cosmetic formulations. GHS hazards: H315, H317 (skin sensitizer Cat 1), H319. If encountered in a cosmetic context, likely refers to a fully cured/polymerized acrylate system, not the free monomer. Verify polymerization state and residual monomer levels The EU classifies Tripropylene Glycol Acrylate as "restricted". Safety rating: POOR.

Is Tripropylene Glycol Acrylate allowed in the EU?

Tripropylene Glycol Acrylate EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does Tripropylene Glycol Acrylate do in cosmetics?

Tripropylene Glycol Acrylate functions as: UV-curable reactive diluent/crosslinker — primarily industrial use in radiation-curing coatings, inks, adhesives. It is classified as a cosmetic ingredient in our database. CAS number: 42978-66-5 (Tripropylene Glycol Diacrylate — the most common commercial form).

What is the Margin of Safety for Tripropylene Glycol Acrylate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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