Is Ammonium Acetate safe in cosmetics?
Ammonium Acetate has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Ammonium Acetate
Also known as: Acetic acid, ammonium salt, EINECS 211-162-9, UNII-RRE756S6Q2, AcONH4, CH3CO2NH4 (+8 more)
Ammonium Acetate (CAS 631-61-8) is a cosmetic cosmetic ingredient functioning as Catalyst; Thickening agent; pH regulating agent. NOAEL 0.64 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 631-61-8 →
Auto-generated CPSR Part A draft with source citations
Function
Catalyst; Thickening agent; pH regulating agent
Safety Rating
GOOD
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted; listed in VCRP. No specific FDA restrictions
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Ammonium Acetate.
Calculate MoS for your specific formulation with the MoS Calculator.
Pre-Calculated Safety Assessment
Pre-calculated NOAEL → SED → MoS audit trail for Ammonium Acetate across SCCS product categories, with measured dermal absorption where available.
EPA ToxValDB — Toxicity Values
10 toxicity values from EPA ToxValDB (aggregated from CCTE, HPV, ToxRefDB, IRIS, and other regulatory dossiers).
| Endpoint | Value | Species | Route | Duration | Source |
|---|---|---|---|---|---|
| LOEL | =200000 ppm | Rat | oral | short-term | ECOTOX |
| LOEL | =1.92 mg/kg-day | Rat | oral | subchronic | ECOTOX |
| LOEL | =20 % | Rat | oral | chronic | ECOTOX |
| NOEL | =20 % | Rat | oral | chronic | ECOTOX |
| LOEL | =200000 ppm | Rat | multiple | short-term | ECOTOX |
| LOEL | =20 g/dl | Rat | oral | short-term | ECOTOX |
| LOEL | =20 g/dl | Rat | oral | short-term | ECOTOX |
| LOEL | =20 g/dl | Rat | oral | short-term | ECOTOX |
| NOEL | =20 g/dl | Rat | oral | short-term | ECOTOX |
| LOEL | =200000 ppm | Rat | oral | short-term | ECOTOX |
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
1,000 - 10,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Catalyst
Thickening agent
pH regulating agent
Regulatory List Membership (1)
FDA Substances Added to Food (EAFUS)
Expert Verdict
Expert safety assessment and concern-level summary for Ammonium Acetate.
Regulatory Flags
fda_food_additive
jecfa_safe
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to Ammonium Acetate by CAS number or substance name.
Studies
27
Lowest NOAEL
54 mg/kg bw/day
Highest NOAEL
4293 mg/kg bw/day
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip
Known Synonyms
Acetic acid, ammonium salt
EINECS 211-162-9
UNII-RRE756S6Q2
AcONH4
CH3CO2NH4
CH3COONH4
E 264
E-264
E264
INS No. 264
NH4OAc
ammonium ethanoate
azanium acetate
Chemical Function
pH regulating agent
Catalyst
Thickening agent
Regulatory Lists
Canada; consumer_product; Substances in Products - Canada (4/2014)
inert_ingredient; Pesticides
active_ingredient; Europe; Pesticides
inert_ingredient; non_food_use; Pesticides
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
fracking; water
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Ammonium Acetate allowed in the EU?
Ammonium Acetate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Ammonium Acetate do in cosmetics?
Ammonium Acetate functions as: Catalyst; Thickening agent; pH regulating agent. It is classified as a cosmetic ingredient in our database. CAS number: 631-61-8.
Is Ammonium Acetate used outside cosmetics?
Ammonium Acetate also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Ammonium Acetate compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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