Tropolone

INCI: TROPOLONE

CAS Number
533-75-5
Function
Skin Conditioning
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Not specifically regulated for cosmetics; permitted under general provisions

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Strong metal chelator (complexes with Fe³⁺, Cu²⁺, lanthanides) — potential to disrupt metal-dependent skin enzymes ; antimicrobial/antifungal activity suggests biological potency; limited cosmetic safety dossier; hygroscopic and sensitive compound

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Concern Level: Moderate

Frequently Asked Questions

Is Tropolone safe in cosmetics?

Strong metal chelator (complexes with Fe³⁺, Cu²⁺, lanthanides) — potential to disrupt metal-dependent skin enzymes ; antimicrobial/antifungal activity suggests biological potency; limited cosmetic safety dossier; hygroscopic and sensitive compound The EU classifies Tropolone as "permitted". Safety rating: MODERATE.

Is Tropolone allowed in the EU?

Tropolone EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Tropolone do in cosmetics?

Tropolone functions as: Skin Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 533-75-5.

What is the Margin of Safety for Tropolone?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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