Is Ufiprazole safe in cosmetics?
Ufiprazole has a safety rating of "POOR" in our database. EU status: permitted. US status: permitted.
Poor
Cosmetic Ingredient
Ufiprazole
Also known as: 5-Methoxy-2-(((4-methoxy-3,5-dimethyl-2-pyridyl)methyl)thio)benzimidazol, Ufiprazol, Ufiprazolum, UNII-6FFV1V867C
INCI: UFIPRAZOLE
Ufiprazole (CAS 73590-85-9) is a cosmetic cosmetic ingredient functioning as Skin conditioning (per CosIng listing); chemically it is omeprazole sulfide (a. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 73590-85-9 →
Auto-generated CPSR Part A draft with source citations
Function
Skin conditioning (per CosIng listing); chemically it is omeprazole sulfide (a pharmaceutical precursor/metabolite)
Safety Rating
POOR
Chemistry & Identifiers
IUPAC Name
6-methoxy-2-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methylsulfanyl]-1H-benzimidazole
InChIKey
XURCIPRUUASYLR-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Known as omeprazole sulfide/impurity C — primarily a pharmaceutical substance; no cosmetic monograph; use in cosmetics may trigger FDA drug classification concerns
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Ufiprazole.
Calculate MoS for your specific formulation with the MoS Calculator.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Intermediate
Tonnage Band
Intermediate use only
Substance Type
SUBSTANCE
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for Ufiprazole.
Known Synonyms
5-Methoxy-2-(((4-methoxy-3,5-dimethyl-2-pyridyl)methyl)thio)benzimidazol
Ufiprazol
Ufiprazolum
UNII-6FFV1V867C
Chemical Function
Softener and conditioner
Regulatory Lists
pharmaceutical
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
UFIPRAZOLE
ChEMBL ID
CHEMBL892
Max Phase
2
Frequently Asked Questions
Is Ufiprazole allowed in the EU?
Ufiprazole EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Ufiprazole do in cosmetics?
Ufiprazole functions as: Skin conditioning (per CosIng listing); chemically it is omeprazole sulfide (a pharmaceutical precursor/metabolite). It is classified as a cosmetic ingredient in our database. CAS number: 73590-85-9.
Is Ufiprazole used outside cosmetics?
Ufiprazole also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Ufiprazole compliance across multiple jurisdictions:
Ingredient Decoder
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Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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