Zanthoxylum Zanthoxyloides Bark Extract
INCI: ZANTHOXYLUM ZANTHOXYLOIDES BARK EXTRACT
Regulatory Status
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Safety Data
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Expert Verdict
Contains bioactive alkaloids with cytotoxic properties (fagaronine is an antileukemic agent); significant data gap — no CIR/SCCS review; potential for phototoxicity from furanocoumarins common in Rutaceae; requires comprehensive supplier safety dossier
Regulatory Flags
Frequently Asked Questions
Is Zanthoxylum Zanthoxyloides Bark Extract safe in cosmetics?
Contains bioactive alkaloids with cytotoxic properties (fagaronine is an antileukemic agent); significant data gap — no CIR/SCCS review; potential for phototoxicity from furanocoumarins common in Rutaceae; requires comprehensive supplier safety dossier The EU classifies Zanthoxylum Zanthoxyloides Bark Extract as "permitted". Safety rating: MODERATE.
Is Zanthoxylum Zanthoxyloides Bark Extract allowed in the EU?
Zanthoxylum Zanthoxyloides Bark Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Zanthoxylum Zanthoxyloides Bark Extract do in cosmetics?
Zanthoxylum Zanthoxyloides Bark Extract functions as: Skin protecting, antimicrobial (traditional use as "toothache bark"). It is classified as a cosmetic ingredient in our database. CAS number: 90131-93-2 (Zanthoxylum zanthoxyloides extract, generic).
What is the Margin of Safety for Zanthoxylum Zanthoxyloides Bark Extract?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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