OralParenteralDosed ingredientTherapeutic flag Cosmetic cross-reference

Diphenhydramine Hydrochloride

CAS 147-24-0

Diphenhydramine Hydrochloride (CAS 147-24-0) is a Phase 4 pharmaceutical compound with 3 bioactivity targets and 9 adverse event associations.

SOURCE NLM DailyMed
Label records
0
SOURCE EMBL-EBI ChEMBL
Bioactivity
3
SOURCE DrugCentral
Adverse signals
9
SOURCE IUPHAR/BPS
PubMed IDs
0
SOURCE EMBL-EBI ChEMBL B25820EEF0F0

Compound Identity

Matched identifiers and naming fields for the pharmaceutical compound record.

Primary Name
Diphenhydramine Hydrochloride
CAS Number
147-24-0
UNII
TC2D6JAD40
InChIKey
PCHPORCSPXIHLZ-UHFFFAOYSA-N
ChEMBL ID
CHEMBL1620
Molecule Type
Small molecule
Source Match
EMBL-EBI ChEMBL (INCHIKEY)
Synonyms and normalized names
DIPHENHYDRAMINE HCL
dosed ingredientoralparenteraltherapeutic flag
SOURCE EMBL-EBI ChEMBL B25820EEF0F0

Clinical Development Phase

Highest clinical development phase rendered from the matched compound identifier rows.

Phase 4 (Approved)
Approved or marketed human pharmaceutical use is represented in the source phase field.
ChEMBL CHEMBL1620 | Small molecule
SOURCE Ingredients table / CosIng profile same-CAS cross-reference

Cross-Reference to Cosmetics

Same-CAS ingredient record found in the cosmetics vertical.

This substance also has a cosmetic safety profile →
SOURCE EMBL-EBI ChEMBL 3 bioactivity rows

Bioactivity & Target Interactions

Target-level activity records with assay counts, activity type, and measured value where present.

TargetActivity ValueAssaysOrganism
- GI50 94017.3518181818 nM 55 -
- Potency 20976.635714285712 nM 31 -
- IC50 2063.4775 nM 4 -
SOURCE NLM RxNorm 7 name rows

Drug Names / RxNorm

Normalized drug-name vocabulary rows, RxCUIs, and source abbreviations.

NameRxCUI TypeSource
DIPHENHYDRAMINE HCL 1362 SU MTHSPL
Diphenhydramine Hydrochloride 1362 SU MTHSPL
diphenhydramine hydrochloride 1362 SU MTHSPL
DIPHENHYDRAMINE HYDROCHLORIDE 1362 SU MTHSPL
Diphenhydramine hydrochloride 1362 SU MTHSPL
diphenhydramine hydrochloride 1362 PIN RXNORM
diphenhydrAMINE hydrochloride 1362 TMSY RXNORM
SOURCE Rendered pharma page rows FAQPage JSON-LD

Frequently Asked Questions

Short answers generated only from the same visible source-linked rows on this page.

What is Diphenhydramine Hydrochloride used for in pharmaceutical contexts?

Diphenhydramine Hydrochloride (CAS 147-24-0) is rendered as a pharmaceutical compound from the matched source rows; no DailyMed product-name rows are present in this page query.

What are the known adverse events for Diphenhydramine Hydrochloride?

Diphenhydramine Hydrochloride has 9 DrugCentral/FAERS adverse event associations. Rendered reaction terms include Blood glucose decreased, Decreased appetite, Diarrhoea, Epistaxis, Loss of consciousness. Signal rows are source-linked records and should not be read as incidence rates or causality conclusions.

Is Diphenhydramine Hydrochloride also used in cosmetics?

Yes. The ingredients table has a same-CAS cosmetic profile for Diphenhydramine HCl with EU status "prohibited".

What clinical phase is Diphenhydramine Hydrochloride in?

Diphenhydramine Hydrochloride is rendered with ChEMBL max phase 4 (approved).