Aminophylline
CAS 317-34-0
Aminophylline (CAS 317-34-0) is a Phase 4 pharmaceutical compound with 5 bioactivity targets and 83 adverse event associations.
Compound Identity
Matched identifiers and naming fields for the pharmaceutical compound record.
Clinical Development Phase
Highest clinical development phase rendered from the matched compound identifier rows.
Cross-Reference to Cosmetics
Same-CAS ingredient record found in the cosmetics vertical.
Bioactivity & Target Interactions
Target-level activity records with assay counts, activity type, and measured value where present.
| Target | Activity | Value | Assays | Organism |
|---|---|---|---|---|
| - | IC50 | 31542.078461538462 nM | 13 | - |
| - | Potency | 12965.828571428572 nM | 6 | - |
| - | AC50 | 31622.78 nM | 1 | - |
| - | EC50 | 50 nM | 1 | - |
| - | Kd | 47.86 nM | 1 | - |
Drug Names / RxNorm
Normalized drug-name vocabulary rows, RxCUIs, and source abbreviations.
| Name | RxCUI | Type | Source |
|---|---|---|---|
| AMINOPHYLLINE | 689 | SU | MTHSPL |
| aminophylline | 689 | IN | RXNORM |
Side Effects
SIDER side-effect terms mapped to the drug or same-CAS compound identity.
| Side Effect | Drug Name | MedDRA Type | Concept ID |
|---|---|---|---|
| Abdominal cramps | aminophylline | LLT | C0000729 |
| Abdominal pain | aminophylline | PT | C0000737 |
| Abdominal pain | aminophylline | LLT | C0000737 |
| Abdominal pain | aminophylline | PT | C0000737 |
| Abdominal pain upper | aminophylline | PT | C0232492 |
| Acute overdose | aminophylline | LLT | C1963951 |
| Agitation | aminophylline | LLT | C0085631 |
| Agitation | aminophylline | PT | C0085631 |
| Agitation | aminophylline | PT | C0085631 |
| Albuminuria | aminophylline | LLT | C0001925 |
| Albuminuria | aminophylline | PT | C0001925 |
| Anorexia | aminophylline | LLT | C0003123 |
| Anxiety | aminophylline | LLT | C0003467 |
| Anxiety | aminophylline | PT | C0003467 |
| Arrhythmia | aminophylline | LLT | C0003811 |
| Arrhythmia | aminophylline | PT | C0003811 |
| Atrial fibrillation | aminophylline | LLT | C0004238 |
| Atrial fibrillation | aminophylline | PT | C0004238 |
| Atrial tachycardia | aminophylline | PT | C0546959 |
| Body temperature increased | aminophylline | LLT | C0015967 |
| Body temperature increased | aminophylline | PT | C0015967 |
| Bronchial hyperreactivity | aminophylline | PT | C0085129 |
| Cardiac flutter | aminophylline | LLT | C0016385 |
| Cardiac flutter | aminophylline | PT | C0016385 |
| Chronic obstructive pulmonary disease | aminophylline | LLT | C0024117 |
| Chronic obstructive pulmonary disease | aminophylline | PT | C0024117 |
| Convulsion | aminophylline | LLT | C0036572 |
| Convulsion | aminophylline | PT | C0036572 |
| Decreased appetite | aminophylline | PT | C0232462 |
| Dermatitis | aminophylline | LLT | C0011603 |
| Dermatitis | aminophylline | PT | C0011603 |
| Dermatitis | aminophylline | PT | C0011603 |
| Dermatitis contact | aminophylline | LLT | C0011616 |
| Dermatitis contact | aminophylline | PT | C0011616 |
| Dermatitis exfoliative | aminophylline | LLT | C0011606 |
| Dermatitis exfoliative | aminophylline | PT | C0011606 |
| Diarrhoea | aminophylline | LLT | C0011991 |
| Diarrhoea | aminophylline | PT | C0011991 |
| Disorientation | aminophylline | LLT | C0233407 |
| Disorientation | aminophylline | PT | C0233407 |
| Diuresis | aminophylline | LLT | C0012797 |
| Dizziness | aminophylline | LLT | C0012833 |
| Dizziness | aminophylline | PT | C0012833 |
| Dizziness | aminophylline | PT | C0012833 |
| Dyspepsia | aminophylline | PT | C0013395 |
| Epigastric pain | aminophylline | LLT | C0232493 |
| Excitement | aminophylline | LLT | C0233571 |
| Extrasystoles | aminophylline | LLT | C0340464 |
| Extrasystoles | aminophylline | PT | C0340464 |
| Flushing | aminophylline | LLT | C0016382 |
| Flushing | aminophylline | PT | C0016382 |
| Gastrointestinal pain | aminophylline | PT | C0687713 |
| Haematemesis | aminophylline | LLT | C0018926 |
| Haematemesis | aminophylline | PT | C0018926 |
| Haemodynamic instability | aminophylline | LLT | C0948268 |
| Haemodynamic instability | aminophylline | PT | C0948268 |
| Headache | aminophylline | LLT | C0018681 |
| Headache | aminophylline | PT | C0018681 |
| Heartburn | aminophylline | LLT | C0018834 |
| Hyperglycaemia | aminophylline | LLT | C0020456 |
| Hyperglycaemia | aminophylline | PT | C0020456 |
| Hypersensitivity | aminophylline | LLT | C0020517 |
| Hypersensitivity | aminophylline | PT | C0020517 |
| Hypokalaemia | aminophylline | LLT | C0020621 |
| Hypokalaemia | aminophylline | PT | C0020621 |
| Hypotension | aminophylline | LLT | C0020649 |
| Hypotension | aminophylline | PT | C0020649 |
| Insomnia | aminophylline | LLT | C0917801 |
| Insomnia | aminophylline | PT | C0917801 |
| Intoxication | aminophylline | LLT | C0728899 |
| Irritability | aminophylline | LLT | C0022107 |
| Irritability | aminophylline | PT | C0022107 |
| Lightheadedness | aminophylline | LLT | C0220870 |
| Multifocal atrial tachycardia | aminophylline | LLT | C0221158 |
| Nausea | aminophylline | LLT | C0027497 |
| Nausea | aminophylline | PT | C0027497 |
| Nervousness | aminophylline | LLT | C0027769 |
| Nervousness | aminophylline | PT | C0027769 |
| Overdose | aminophylline | PT | C0029944 |
| Palpitations | aminophylline | LLT | C0030252 |
Frequently Asked Questions
Short answers generated only from the same visible source-linked rows on this page.
What is Aminophylline used for in pharmaceutical contexts?
Aminophylline (CAS 317-34-0) is rendered as a pharmaceutical compound from the matched source rows; no DailyMed product-name rows are present in this page query.
What are the known adverse events for Aminophylline?
Aminophylline has 83 DrugCentral/FAERS adverse event associations. Rendered reaction terms include Abdominal discomfort, Alopecia, Amyloid arthropathy, Anaemia, Arthropathy. Signal rows are source-linked records and should not be read as incidence rates or causality conclusions.
Is Aminophylline also used in cosmetics?
Yes. The ingredients table has a same-CAS cosmetic profile for Aminophylline with EU status "prohibited".
What clinical phase is Aminophylline in?
Aminophylline is rendered with ChEMBL max phase 4 (approved).