Honokiol
CAS 35354-74-6
Honokiol (CAS 35354-74-6) is a pharmaceutical compound with 8 bioactivity targets and 29 adverse event associations.
Compound Identity
Matched identifiers and naming fields for the pharmaceutical compound record.
Cross-Reference to Cosmetics
Same-CAS ingredient record found in the cosmetics vertical.
Bioactivity & Target Interactions
Target-level activity records with assay counts, activity type, and measured value where present.
| Target | Activity | Value | Assays | Organism |
|---|---|---|---|---|
| - | IC50 | 30362.293333333335 nM | 84 | - |
| - | MIC | 60.10454545454545 ug.mL-1 | 44 | - |
| - | Potency | 31940.031707317074 nM | 35 | - |
| - | EC50 | 27773.125 nM | 16 | - |
| - | Kd | 12464.285714285714 nM | 7 | - |
| - | IC50 | 5.8999999999999995 ug.mL-1 | 6 | - |
| - | Ki | 4025 nM | 3 | - |
| - | AC50 | 39000 nM | 1 | - |
IUPHAR Ligand-Target Data
Curated ligand-target interaction rows with action, affinity, and literature identifiers.
| Target | Action | Affinity | PubMed |
|---|---|---|---|
| 5-LOX ALOX5 |
Inhibition | 5.380000114440918 pIC50 | 19481465 |
Frequently Asked Questions
Short answers generated only from the same visible source-linked rows on this page.
What is Honokiol used for in pharmaceutical contexts?
Honokiol (CAS 35354-74-6) is rendered as a pharmaceutical compound from the matched source rows; no DailyMed product-name rows are present in this page query.
What are the known adverse events for Honokiol?
Honokiol has 29 DrugCentral/FAERS adverse event associations. Rendered reaction terms include Death, Drug ineffective, Ascites, Fatigue, Haematotoxicity. Signal rows are source-linked records and should not be read as incidence rates or causality conclusions.
Is Honokiol also used in cosmetics?
Yes. The ingredients table has a same-CAS cosmetic profile for Honokiol with EU status "permitted".
What clinical phase is Honokiol in?
No phase 1-4 clinical development badge is rendered for Honokiol because the matched compound identifier rows do not contain a max-phase value.