Dyphylline
CAS 479-18-5
Dyphylline (CAS 479-18-5) is a Phase 4 pharmaceutical compound with 2 bioactivity targets and 35 adverse event associations.
Compound Identity
Matched identifiers and naming fields for the pharmaceutical compound record.
Clinical Development Phase
Highest clinical development phase rendered from the matched compound identifier rows.
Cross-Reference to Cosmetics
Same-CAS ingredient record found in the cosmetics vertical.
Bioactivity & Target Interactions
Target-level activity records with assay counts, activity type, and measured value where present.
| Target | Activity | Value | Assays | Organism |
|---|---|---|---|---|
| - | AC50 | 26035.134210526314 nM | 38 | - |
| - | Potency | 30169.3 nM | 12 | - |
| - | IC50 | 19976.309999999998 nM | 1 | - |
| cGMP-inhibited 3',5'-cyclic phosphodiesterase A Enzyme |
INHIBITOR | - | - | Homo sapiens |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B Enzyme |
INHIBITOR | - | - | Homo sapiens |
Side Effects
SIDER side-effect terms mapped to the drug or same-CAS compound identity.
| Side Effect | Drug Name | MedDRA Type | Concept ID |
|---|---|---|---|
| Abdominal pain upper | dyphylline | PT | C0232492 |
| Agitation | dyphylline | LLT | C0085631 |
| Agitation | dyphylline | PT | C0085631 |
| Albuminuria | dyphylline | LLT | C0001925 |
| Albuminuria | dyphylline | PT | C0001925 |
| Convulsion | dyphylline | LLT | C0036572 |
| Convulsion | dyphylline | PT | C0036572 |
| Diarrhoea | dyphylline | LLT | C0011991 |
| Diarrhoea | dyphylline | PT | C0011991 |
| Diuresis | dyphylline | LLT | C0012797 |
| Epigastric pain | dyphylline | LLT | C0232493 |
| Extrasystoles | dyphylline | LLT | C0340464 |
| Extrasystoles | dyphylline | PT | C0340464 |
| Flushing | dyphylline | LLT | C0016382 |
| Flushing | dyphylline | PT | C0016382 |
| Haematemesis | dyphylline | LLT | C0018926 |
| Haematemesis | dyphylline | PT | C0018926 |
| Haematuria | dyphylline | PT | C0018965 |
| Headache | dyphylline | LLT | C0018681 |
| Headache | dyphylline | PT | C0018681 |
| Hyperglycaemia | dyphylline | LLT | C0020456 |
| Hyperglycaemia | dyphylline | PT | C0020456 |
| Hypotension | dyphylline | LLT | C0020649 |
| Hypotension | dyphylline | PT | C0020649 |
| Inappropriate antidiuretic hormone secretion | dyphylline | LLT | C0021141 |
| Inappropriate antidiuretic hormone secretion | dyphylline | PT | C0021141 |
| Insomnia | dyphylline | LLT | C0917801 |
| Insomnia | dyphylline | PT | C0917801 |
| Irritability | dyphylline | LLT | C0022107 |
| Irritability | dyphylline | PT | C0022107 |
| Microscopic hematuria | dyphylline | LLT | C0239937 |
| Muscle twitching | dyphylline | LLT | C0231530 |
| Muscle twitching | dyphylline | PT | C0231530 |
| Nausea | dyphylline | LLT | C0027497 |
| Nausea | dyphylline | PT | C0027497 |
| Palpitations | dyphylline | LLT | C0030252 |
| Palpitations | dyphylline | PT | C0030252 |
| Polyuria | dyphylline | PT | C0032617 |
| Shock | dyphylline | LLT | C0036974 |
| Shock | dyphylline | PT | C0036974 |
| Tachycardia | dyphylline | LLT | C0039231 |
| Tachycardia | dyphylline | PT | C0039231 |
| Tachypnoea | dyphylline | LLT | C0231835 |
| Tachypnoea | dyphylline | PT | C0231835 |
| Ventricular arrhythmia | dyphylline | LLT | C0085612 |
| Ventricular arrhythmia | dyphylline | PT | C0085612 |
| Vomiting | dyphylline | LLT | C0042963 |
| Vomiting | dyphylline | PT | C0042963 |
Frequently Asked Questions
Short answers generated only from the same visible source-linked rows on this page.
What is Dyphylline used for in pharmaceutical contexts?
Dyphylline (CAS 479-18-5) is rendered as a pharmaceutical compound from the matched source rows; no DailyMed product-name rows are present in this page query.
What are the known adverse events for Dyphylline?
Dyphylline has 35 DrugCentral/FAERS adverse event associations. Rendered reaction terms include Hyperglycaemic hyperosmolar nonketotic syndrome, Type 1 diabetes mellitus, Bronchitis, Cough, Dizziness postural. Signal rows are source-linked records and should not be read as incidence rates or causality conclusions.
Is Dyphylline also used in cosmetics?
Yes. The ingredients table has a same-CAS cosmetic profile for Dyphylline with EU status "permitted".
What clinical phase is Dyphylline in?
Dyphylline is rendered with ChEMBL max phase 4 (approved).
What bioactivity targets are documented for Dyphylline?
Dyphylline has 5 bioactivity rows in this page query. Rendered target entries include cGMP-inhibited 3',5'-cyclic phosphodiesterase A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B.