Dyphylline

INCI: DYPHYLLINE

CAS Number
479-18-5
Function
Phosphodiesterase inhibitor and adenosine receptor antagonist with primary pharmaceutical use as a bronchodilator; not a standard cosmetic function
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status restricted
US Notes Recognized as a drug under 21 CFR and listed as a bronchodilator. Cosmetic use would likely trigger drug/cosmetic dual classification under the FD&C Act.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Dyphylline is a pharmaceutical bronchodilator with poor safety profile and no established margin of safety; cosmetic use would likely require drug classification.

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Concern Level: High

Frequently Asked Questions

Is Dyphylline safe in cosmetics?

Dyphylline is a pharmaceutical bronchodilator with poor safety profile and no established margin of safety; cosmetic use would likely require drug classification. The EU classifies Dyphylline as "permitted". Safety rating: POOR.

Is Dyphylline allowed in the EU?

Dyphylline EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Dyphylline do in cosmetics?

Dyphylline functions as: Phosphodiesterase inhibitor and adenosine receptor antagonist with primary pharmaceutical use as a bronchodilator; not a standard cosmetic function. It is classified as a cosmetic ingredient in our database. CAS number: 479-18-5.

What is the Margin of Safety for Dyphylline?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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