Cosmetic cross-reference

Apigenin

CAS 520-36-5

Apigenin (CAS 520-36-5) is a pharmaceutical compound with 11 bioactivity targets and 0 adverse event associations.

SOURCE NLM DailyMed
Label records
0
SOURCE EMBL-EBI ChEMBL
Bioactivity
11
SOURCE DrugCentral
Adverse signals
0
SOURCE IUPHAR/BPS
PubMed IDs
2
SOURCE EMBL-EBI ChEMBL B25820EEF0F0

Compound Identity

Matched identifiers and naming fields for the pharmaceutical compound record.

Primary Name
Apigenin
CAS Number
520-36-5
UNII
7V515PI7F6
InChIKey
KZNIFHPLKGYRTM-UHFFFAOYSA-N
ChEMBL ID
CHEMBL28
Molecule Type
Small molecule
Source Match
EMBL-EBI ChEMBL (INCHIKEY)
natural product
SOURCE Ingredients table / CosIng profile same-CAS cross-reference

Cross-Reference to Cosmetics

Same-CAS ingredient record found in the cosmetics vertical.

SOURCE EMBL-EBI ChEMBL 11 bioactivity rows

Bioactivity & Target Interactions

Target-level activity records with assay counts, activity type, and measured value where present.

TargetActivity ValueAssaysOrganism
- IC50 19300.632091836735 nM 192 -
- Potency 21758.139600000002 nM 155 -
- GI50 27241.293962264153 nM 53 -
- MIC 85.71923076923076 ug.mL-1 26 -
- EC50 25646.4 nM 25 -
- Ki 17677.33095238095 nM 21 -
- IC50 18.583529411764708 ug.mL-1 17 -
- AC50 4190.455 nM 4 -
- Kd 13127.5 nM 4 -
- EC50 6.73 ug.mL-1 2 -
- MIC 6000 nM 1 -
SOURCE IUPHAR/BPS 5 interactions

IUPHAR Ligand-Target Data

Curated ligand-target interaction rows with action, affinity, and literature identifiers.

TargetAction AffinityPubMed
CFTR
CFTR
Potentiation - -
CYP1A1
CYP1A1
Inhibition 6.409999847412109 pKi 21482471
CYP1B1
CYP1B1
Inhibition 7.190000057220459 pKi 21482471
acetylcholinesterase (Yt blood group)
ACHE
Inhibition 7.920000076293945 pIC50 -
transthyretin
TTR
Binding 6.599999904632568 pKd 26214366
SOURCE NLM RxNorm 2 name rows

Drug Names / RxNorm

Normalized drug-name vocabulary rows, RxCUIs, and source abbreviations.

NameRxCUI TypeSource
APIGENIN 1368130 SU MTHSPL
apigenin 1368130 IN RXNORM
SOURCE Rendered pharma page rows FAQPage JSON-LD

Frequently Asked Questions

Short answers generated only from the same visible source-linked rows on this page.

What is Apigenin used for in pharmaceutical contexts?

Apigenin (CAS 520-36-5) is rendered as a pharmaceutical compound from the matched source rows; no DailyMed product-name rows are present in this page query.

What are the known adverse events for Apigenin?

No adverse-event association or SIDER side-effect rows are rendered for Apigenin in this page query. Signal rows are source-linked records and should not be read as incidence rates or causality conclusions.

Is Apigenin also used in cosmetics?

Yes. The ingredients table has a same-CAS cosmetic profile for Apigenin with EU status "permitted".

What clinical phase is Apigenin in?

No phase 1-4 clinical development badge is rendered for Apigenin because the matched compound identifier rows do not contain a max-phase value.