Cosmetic cross-reference

Histidine

CAS 71-00-1

Histidine (CAS 71-00-1) is a Phase 2 pharmaceutical compound with 1 bioactivity target and 2 adverse event associations.

SOURCE NLM DailyMed

Label records

SOURCE EMBL-EBI ChEMBL

Bioactivity

SOURCE DrugCentral

Adverse signals

SOURCE IUPHAR/BPS

PubMed IDs

SOURCE EMBL-EBI ChEMBL B25820EEF0F0

Compound Identity

Matched identifiers and naming fields for the pharmaceutical compound record.

Primary Name

Histidine

CAS Number

71-00-1

UNII

4QD397987E

InChIKey

HNDVDQJCIGZPNO-YFKPBYRVSA-N

ChEMBL ID

CHEMBL17962

Molecule Type

Small molecule

Source Match

EMBL-EBI ChEMBL (INCHIKEY)

Synonyms and normalized names

L-histidine

natural product

SOURCE EMBL-EBI ChEMBL B25820EEF0F0

Clinical Development Phase

Highest clinical development phase rendered from the matched compound identifier rows.

Phase 2

Mid-stage clinical development phase from the compound identifier source.

ChEMBL CHEMBL17962 | Small molecule

SOURCE Ingredients table / CosIng profile same-CAS cross-reference

Cross-Reference to Cosmetics

Same-CAS ingredient record found in the cosmetics vertical.

This substance also has a cosmetic safety profile →

SOURCE EMBL-EBI ChEMBL 5 bioactivity rows

Bioactivity & Target Interactions

Target-level activity records with assay counts, activity type, and measured value where present.

Target	Activity	Value	Assays	Organism
-	Potency	10386.55 nM	6	-
-	EC50	38666.666666666664 nM	3	-
-	IC50	13333.333333333334 nM	3	-
-	AC50	794.33 nM	1	-
Large neutral amino acids transporter small subunit 1 Transporter	IC50	4.7	-	Homo sapiens

SOURCE DrugCentral 1 association

Adverse Event Associations

DrugCentral / FAERS disproportionality signal rows matched to this compound.

Reaction PT	Drug AE	LLR	MedDRA
Foetal growth restriction	15	67.975	10070531

Association rows are source-linked signal records, not incidence rates or clinical causality claims.

SOURCE IUPHAR/BPS 4 interactions

IUPHAR Ligand-Target Data

Curated ligand-target interaction rows with action, affinity, and literature identifiers.

Target	Action	Affinity	PubMed
carbonic anhydrase 1 CA1	Activation	-	16807956
carbonic anhydrase 14 CA14	Activation	-	16807956
carbonic anhydrase 5A CA5A	Activation	-	16807956
carbonic anhydrase 7 CA7	Activation	-	16807956

SOURCE NLM RxNorm 5 name rows

Drug Names / RxNorm

Normalized drug-name vocabulary rows, RxCUIs, and source abbreviations.

Name	RxCUI	Type	Source
Histidine	5340	SU	MTHSPL
HISTIDINE	5340	SU	MTHSPL
histidine	5340	SU	MTHSPL
histidine	5340	IN	RXNORM
L-histidine	5340	SY	RXNORM

SOURCE Rendered pharma page rows FAQPage JSON-LD

Frequently Asked Questions

Short answers generated only from the same visible source-linked rows on this page.

What is Histidine used for in pharmaceutical contexts?

Histidine (CAS 71-00-1) is rendered as a pharmaceutical compound from the matched source rows; no DailyMed product-name rows are present in this page query.

What are the known adverse events for Histidine?

Histidine has 2 DrugCentral/FAERS adverse event associations. Rendered reaction terms include Foetal growth restriction, Dry eye. Signal rows are source-linked records and should not be read as incidence rates or causality conclusions.

Is Histidine also used in cosmetics?

Yes. The ingredients table has a same-CAS cosmetic profile for L-Histidine with EU status "permitted".

What clinical phase is Histidine in?

Histidine is rendered with ChEMBL max phase 2.

What bioactivity targets are documented for Histidine?

Histidine has 5 bioactivity rows in this page query. Rendered target entries include Large neutral amino acids transporter small subunit 1.