Cosmetic cross-reference
Iron
CAS 7439-89-6
Iron (CAS 7439-89-6) is a pharmaceutical compound with 0 bioactivity targets and 5,257 adverse event associations.
SOURCE
NLM DailyMed
Label records
0
SOURCE
EMBL-EBI ChEMBL
Bioactivity
0
SOURCE
DrugCentral
Adverse signals
5,257
SOURCE
IUPHAR/BPS
PubMed IDs
1
SOURCE
DrugCentral
055904D152D6
Compound Identity
Matched identifiers and naming fields for the pharmaceutical compound record.
Primary Name
Iron
CAS Number
7439-89-6
UNII
E1UOL152H7
InChIKey
XEEYBQQBJWHFJM-UHFFFAOYSA-N
DrugCentral Struct ID
4277
Source Match
DrugCentral (CAS), FDA GSRS (UNII)
SOURCE
Ingredients table / CosIng profile
same-CAS cross-reference
Cross-Reference to Cosmetics
Same-CAS ingredient record found in the cosmetics vertical.
SOURCE
DrugCentral
80 associations
Adverse Event Associations
DrugCentral / FAERS disproportionality signal rows matched to this compound.
| Reaction PT | Drug AE | LLR | MedDRA |
|---|---|---|---|
| Blood iron decreased | 205 | 251.017 | 10005619 |
| Colitis ulcerative | 287 | 248.75 | 10009900 |
| Pemphigus | 3 | 238.021 | 10034280 |
| Haemoglobin decreased | 742 | 200.921 | 10018884 |
| Hand deformity | 10 | 180.347 | 10061194 |
| Haematochezia | 371 | 160.086 | 10018836 |
| Glossodynia | 29 | 156.417 | 10018388 |
| Inappropriate schedule of product administration | 527 | 142.909 | 10081572 |
| Drug abuse | 19 | 141.617 | 10013654 |
| Toxicity to various agents | 225 | 135.333 | 10070863 |
| Weight decreased | 994 | 132.176 | 10047895 |
| Pericarditis | 18 | 131.335 | 10034484 |
| Off label use | 2155 | 125.496 | 10053762 |
| Anaemia | 1082 | 118.839 | 10002034 |
| Frequent bowel movements | 181 | 116.281 | 10017367 |
| Systemic lupus erythematosus | 73 | 114.562 | 10042945 |
| Premature labour | 106 | 114.193 | 10036600 |
| Abdominal pain | 949 | 109.282 | 10000081 |
| Duodenal ulcer perforation | 3 | 107.01 | 10013849 |
| Exposure during pregnancy | 470 | 106.792 | 10073513 |
| Contraindicated product administered | 105 | 103.425 | 10078504 |
| Helicobacter infection | 9 | 96.685 | 10054263 |
| Febrile neutropenia | 111 | 95.835 | 10016288 |
| Drug interaction | 273 | 94.378 | 10013710 |
| Heavy menstrual bleeding | 111 | 94.252 | 10085423 |
| Product dose omission issue | 736 | 91.994 | 10084406 |
| Blood pressure fluctuation | 285 | 85.36 | 10005746 |
| Intentional product use issue | 524 | 83.95 | 10076308 |
| Diarrhoea | 1860 | 83.888 | 10012735 |
| Condition aggravated | 1134 | 78.458 | 10010264 |
| Synovitis | 90 | 77.758 | 10042868 |
| Intentional overdose | 26 | 76.874 | 10022523 |
| Neutropenia | 205 | 75.523 | 10029354 |
| Premature delivery | 135 | 74.624 | 10036595 |
| Fatigue | 2062 | 71.495 | 10016256 |
| Heart rate increased | 364 | 70.96 | 10019303 |
| Acute kidney injury | 417 | 70.075 | 10069339 |
| Overdose | 102 | 70.059 | 10033295 |
| Mineral supplementation | 30 | 69.478 | 10053963 |
| Faecal calprotectin increased | 64 | 67.992 | 10072482 |
| Device expulsion | 134 | 67.077 | 10012578 |
| Gastrointestinal tract mucosal pigmentation | 32 | 66.622 | 10057084 |
| Drug intolerance | 253 | 65.662 | 10061822 |
| Nipple swelling | 21 | 62.727 | 10058680 |
| Poor venous access | 108 | 62.615 | 10048737 |
| Clostridium difficile infection | 168 | 61.922 | 10054236 |
| Discomfort | 93 | 61.664 | 10013082 |
| Faeces discoloured | 130 | 60.878 | 10016100 |
| Muscle injury | 9 | 60.131 | 10028314 |
| Folliculitis | 14 | 59.41 | 10016936 |
Association rows are source-linked signal records, not incidence rates or clinical causality claims.
SOURCE
PharmGKB
2 phenotype rows
Pharmacogenomics
Drug-gene phenotype annotations and evidence levels from PharmGKB-mapped rows.
HFE (PA29263) rs1799945
Allele G is associated with decreased risk of mortality (due to sepsis or cardiovascular causes) when treated with epoetin alfa and iron in people with hemodialysis treatment as compared to allele C.
Evidence: -; PMID 18025780
HFE (PA29263) rs1800562
Allele A is associated with decreased risk of mortality (due to sepsis or cardiovascular causes) when treated with epoetin alfa and iron in people with hemodialysis treatment as compared to allele G.
Evidence: -; PMID 18025780
SOURCE
NLM RxNorm
4 name rows
Drug Names / RxNorm
Normalized drug-name vocabulary rows, RxCUIs, and source abbreviations.
| Name | RxCUI | Type | Source |
|---|---|---|---|
| IRON | 90176 | SU | MTHSPL |
| Iron | 90176 | SU | MTHSPL |
| iron | 90176 | SU | MTHSPL |
| iron | 90176 | IN | RXNORM |
SOURCE
SIDER
80 side-effect rows
Side Effects
SIDER side-effect terms mapped to the drug or same-CAS compound identity.
| Side Effect | Drug Name | MedDRA Type | Concept ID |
|---|---|---|---|
| Abdominal pain | iron | LLT | C0000737 |
| Abdominal pain | iron | PT | C0000737 |
| Acute coronary syndrome | iron | PT | C0948089 |
| Anaphylactic shock | iron | LLT | C0002792 |
| Anaphylactic shock | iron | PT | C0002792 |
| Anaphylactic shock | iron | PT | C0002792 |
| Anaphylactoid reaction | iron | LLT | C0340865 |
| Anaphylactoid reaction | iron | PT | C0340865 |
| Angiopathy | iron | LLT | C0042373 |
| Angiopathy | iron | PT | C0042373 |
| Anxiety | iron | LLT | C0003467 |
| Anxiety | iron | PT | C0003467 |
| Arthralgia | iron | LLT | C0003862 |
| Arthralgia | iron | PT | C0003862 |
| Arthritis | iron | LLT | C0003864 |
| Arthritis | iron | PT | C0003864 |
| Asthenia | iron | LLT | C0004093 |
| Asthenia | iron | PT | C0004093 |
| Asthenia | iron | PT | C0004093 |
| Asthma | iron | LLT | C0004096 |
| Asthma | iron | PT | C0004096 |
| Back pain | iron | LLT | C0004604 |
| Back pain | iron | PT | C0004604 |
| Blood iron abnormal | iron | LLT | C0853227 |
| Blood iron abnormal | iron | PT | C0853227 |
| Body temperature increased | iron | LLT | C0015967 |
| Body temperature increased | iron | PT | C0015967 |
| Bone pain | iron | LLT | C0151825 |
| Bone pain | iron | PT | C0151825 |
| Bronchospasm | iron | LLT | C0006266 |
| Bronchospasm | iron | PT | C0006266 |
| Burning sensation | iron | LLT | C0085624 |
| Burning sensation | iron | PT | C0085624 |
| Cardiac failure congestive | iron | LLT | C0018802 |
| Cardiac failure congestive | iron | PT | C0018802 |
| Cardiac murmur | iron | LLT | C0018808 |
| Cardiac murmur | iron | PT | C0018808 |
| Cardio-respiratory arrest | iron | LLT | C0600228 |
| Cardio-respiratory arrest | iron | PT | C0600228 |
| Catheter site infection | iron | LLT | C1112210 |
| Catheter site infection | iron | PT | C1112210 |
| Chest pain | iron | LLT | C0008031 |
| Chest pain | iron | PT | C0008031 |
| Chills | iron | LLT | C0085593 |
| Chills | iron | PT | C0085593 |
| Conjunctivitis | iron | LLT | C0009763 |
| Conjunctivitis | iron | PT | C0009763 |
| Constipation | iron | LLT | C0009806 |
| Constipation | iron | PT | C0009806 |
| Convulsion | iron | LLT | C0036572 |
| Convulsion | iron | PT | C0036572 |
| Cough | iron | LLT | C0010200 |
| Cough | iron | PT | C0010200 |
| Cramp muscle | iron | LLT | C0026821 |
| Dermatitis | iron | PT | C0011603 |
| Diarrhoea | iron | LLT | C0011991 |
| Diarrhoea | iron | PT | C0011991 |
| Discomfort | iron | PT | C0234215 |
| Dizziness | iron | LLT | C0012833 |
| Dizziness | iron | PT | C0012833 |
| Dysgeusia | iron | LLT | C0013378 |
| Dysgeusia | iron | PT | C0013378 |
| Dyspnoea | iron | LLT | C0013404 |
| Dyspnoea | iron | PT | C0013404 |
| Dyspnoea | iron | PT | C0013404 |
| Dyspnoea exacerbated | iron | LLT | C0853326 |
| Ear and labyrinth disorders | iron | - | C0851354 |
| Ear pain | iron | LLT | C0013456 |
| Ear pain | iron | PT | C0013456 |
| Erythema | iron | LLT | C0041834 |
| Erythema | iron | PT | C0041834 |
| Eye disorder | iron | LLT | C0015397 |
| Eye disorder | iron | PT | C0015397 |
| Faecal occult blood positive | iron | LLT | C0266813 |
| Fatigue | iron | LLT | C0015672 |
| Fatigue | iron | PT | C0015672 |
| Feeling abnormal | iron | PT | C1443060 |
| Feeling abnormal | iron | LLT | C1443060 |
| Feeling abnormal | iron | PT | C1443060 |
| Feeling hot | iron | LLT | C2939147 |
SOURCE
Rendered pharma page rows
FAQPage JSON-LD
Frequently Asked Questions
Short answers generated only from the same visible source-linked rows on this page.
What is Iron used for in pharmaceutical contexts?
Iron (CAS 7439-89-6) is rendered as a pharmaceutical compound from the matched source rows; no DailyMed product-name rows are present in this page query.
What are the known adverse events for Iron?
Iron has 5,257 DrugCentral/FAERS adverse event associations. Rendered reaction terms include Blood iron decreased, Colitis ulcerative, Pemphigus, Haemoglobin decreased, Hand deformity. Signal rows are source-linked records and should not be read as incidence rates or causality conclusions.
Is Iron also used in cosmetics?
Yes. The ingredients table has a same-CAS cosmetic profile for Iron Powder with EU status "permitted".
What clinical phase is Iron in?
No phase 1-4 clinical development badge is rendered for Iron because the matched compound identifier rows do not contain a max-phase value.