Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
10 study endpoints found for Iron Powder. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 3000 mg/kg bw/day | oral | rat | Special Toxicology Study | COSMOS_DB |
| NOAEL | 500 mg/kg bw/day | oral | rat | Special Toxicology Study | COSMOS_DB |
| NOAEL | 1000 mg/kg bw/day | oral | rat | Special Toxicology Study | COSMOS_DB |
| NOAEL | 130 mg/kg bw/day | oral | rat | Chronic | COSMOS_DB |
| NOAEL | 3000 mg/kg bw/day | oral | rat | Special Toxicology Study | COSMOS_DB |
| NOAEL | 3000 mg/kg bw/day | oral | rat | Special Toxicology Study | COSMOS_DB |
| NOAEL | 3000 mg/kg bw/day | oral | rat | Special Toxicology Study | COSMOS_DB |
| NOAEL | 2500 mg/kg bw/day | oral | rat | Special Toxicology Study | COSMOS_DB |
| NOAEL | 173 mg/kg bw/day | oral | rat | Short Term Toxicity | COSMOS_DB |
| NOAEL | 173 mg/kg bw/day | oral | rat | Short Term Toxicity | COSMOS_DB |
Expert Verdict
Iron Powder is classified as a skin sensitizer (H317) and respiratory irritant (H335) with flammability concerns (H228); dust inhalation and particle size effects, particularly for nanoparticles, require careful safety assessment and limit suitability for leave-on products.
Regulatory Flags
Frequently Asked Questions
Is Iron Powder safe in cosmetics?
Iron Powder is classified as a skin sensitizer (H317) and respiratory irritant (H335) with flammability concerns (H228); dust inhalation and particle size effects, particularly for nanoparticles, require careful safety assessment and limit suitability for leave-on products. The EU classifies Iron Powder as "permitted". Safety rating: MODERATE. 10 toxicological study endpoint(s) are available in our database.
Is Iron Powder allowed in the EU?
Iron Powder EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Iron Powder do in cosmetics?
Iron Powder functions as: Bulking agent. It is classified as a cosmetic ingredient in our database. CAS number: 7439-89-6.
What is the Margin of Safety for Iron Powder?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Iron Powder?
The NOAEL (No Observed Adverse Effect Level) for Iron Powder is 3000 mg/kg bw/day based on a Special Toxicology Study study via oral route in rat. A total of 10 study endpoints are available. Source: COSMOS_DB.
Compliance Tools
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