TopicalDosed ingredient Cosmetic cross-reference

Nitrogen

CAS 7727-37-9

Nitrogen (CAS 7727-37-9) is a Phase 4 pharmaceutical compound with 0 bioactivity targets and 558 adverse event associations.

SOURCE NLM DailyMed

Label records

SOURCE EMBL-EBI ChEMBL

Bioactivity

SOURCE DrugCentral

Adverse signals

558

SOURCE IUPHAR/BPS

PubMed IDs

SOURCE EMBL-EBI ChEMBL B25820EEF0F0

Compound Identity

Matched identifiers and naming fields for the pharmaceutical compound record.

Primary Name

Nitrogen

CAS Number

7727-37-9

UNII

N762921K75

InChIKey

IJGRMHOSHXDMSA-UHFFFAOYSA-N

ChEMBL ID

CHEMBL142438

Molecule Type

Small molecule

Source Match

EMBL-EBI ChEMBL (INCHIKEY)

dosed ingredientnatural producttopical

SOURCE EMBL-EBI ChEMBL B25820EEF0F0

Clinical Development Phase

Highest clinical development phase rendered from the matched compound identifier rows.

Phase 4 (Approved)

Approved or marketed human pharmaceutical use is represented in the source phase field.

ChEMBL CHEMBL142438 | Small molecule

SOURCE Ingredients table / CosIng profile same-CAS cross-reference

Cross-Reference to Cosmetics

Same-CAS ingredient record found in the cosmetics vertical.

This substance also has a cosmetic safety profile →

SOURCE DrugCentral 80 associations

Adverse Event Associations

DrugCentral / FAERS disproportionality signal rows matched to this compound.

Reaction PT	Drug AE	LLR	MedDRA
Dyspnoea	3021	1364.976	10013968
Pulmonary arterial hypertension	549	1098.628	10064911
Oxygen saturation decreased	949	949.015	10033318
Pulmonary hypertension	531	737.037	10037400
Right ventricular failure	380	695.262	10039163
Oxygen consumption increased	230	662.569	10059168
Hypoxia	621	577.933	10021143
Fluid retention	517	524.036	10016807
Dyspnoea exertional	535	475.118	10013971
Chronic obstructive pulmonary disease	546	466.437	10009033
Respiratory failure	761	464.615	10038695
Drug ineffective	557	386.191	10013709
Pneumonia	1644	364.65	10035664
Hypervolaemia	285	290.51	10020919
Oxygen therapy	108	280.937	10078798
Transfusion	209	280.073	10066152
Acute respiratory failure	314	264.047	10001053
Pain in jaw	285	250.654	10033433
Concomitant disease aggravated	151	220.564	10010253
Nasal congestion	337	209.554	10028735
Toxicity to various agents	92	206.943	10070863
Completed suicide	6	201.691	10010144
Contraindicated product administered	14	201.042	10078504
Cough	906	198.981	10011224
Oedema peripheral	683	194.149	10030124
Pulmonary oedema	346	193.987	10037423
Alopecia	69	183.052	10001760
Treatment failure	22	180.984	10066901
Arthropathy	27	179.325	10003285
Rheumatoid arthritis	40	176.75	10039073
Cardiac failure	471	175.271	10007554
Therapeutic product effect decreased	20	162.85	10082201
Pulmonary arterial pressure increased	83	161.671	10037324
Drug intolerance	88	159.721	10061822
Glossodynia	11	150.45	10018388
Productive cough	315	150.032	10036790
Haemoptysis	237	148.131	10018964
Hand deformity	7	143.032	10061194
Lung transplant	78	142.57	10025127
Systemic lupus erythematosus	29	135.887	10042945
Oedema	370	133.107	10030095
Hypercapnia	93	130.323	10020591
Retinopathy of prematurity	43	129.077	10038933
Catheter site erythema	74	127.015	10052264
Rash	368	126.709	10037844
Joint swelling	125	121.129	10023232
Blood pressure decreased	307	117.671	10005734
Chest pain	631	116.148	10008479
Catheter site pruritus	53	115.873	10052270
Drug abuse	13	114.774	10013654

Association rows are source-linked signal records, not incidence rates or clinical causality claims.

SOURCE NLM RxNorm 4 name rows

Drug Names / RxNorm

Normalized drug-name vocabulary rows, RxCUIs, and source abbreviations.

Name	RxCUI	Type	Source
NITROGEN	7456	SU	MTHSPL
Nitrogen	7456	SU	MTHSPL
nitrogen	7456	SU	MTHSPL
nitrogen	7456	IN	RXNORM

SOURCE SIDER 80 side-effect rows

Side Effects

SIDER side-effect terms mapped to the drug or same-CAS compound identity.

Side Effect	Drug Name	MedDRA Type	Concept ID
Agranulocytosis	nitrogen	LLT	C0001824
Agranulocytosis	nitrogen	PT	C0001824
Alopecia	nitrogen	LLT	C0002170
Alopecia	nitrogen	PT	C0002170
Amenorrhoea	nitrogen	LLT	C0002453
Amenorrhoea	nitrogen	PT	C0002453
Anaphylactic shock	nitrogen	LLT	C0002792
Anaphylactic shock	nitrogen	PT	C0002792
Anorexia	nitrogen	LLT	C0003123
Aplasia	nitrogen	LLT	C0243065
Aplasia	nitrogen	PT	C0243065
Azoospermia	nitrogen	LLT	C0004509
Azoospermia	nitrogen	PT	C0004509
Azotaemia	nitrogen	LLT	C0242528
Azotaemia	nitrogen	PT	C0242528
Blister	nitrogen	LLT	C0005758
Blister	nitrogen	PT	C0005758
Decreased appetite	nitrogen	PT	C0232462
Depression	nitrogen	LLT	C0011570
Depression	nitrogen	PT	C0011570
Dermatitis	nitrogen	LLT	C0011603
Dermatitis	nitrogen	PT	C0011603
Dermatitis	nitrogen	PT	C0011603
Dermatitis bullous	nitrogen	PT	C0085932
Diarrhoea	nitrogen	LLT	C0011991
Diarrhoea	nitrogen	PT	C0011991
Erythema multiforme	nitrogen	LLT	C0014742
Erythema multiforme	nitrogen	PT	C0014742
Eye injury	nitrogen	LLT	C0015408
Eye injury	nitrogen	PT	C0015408
Haemoglobin	nitrogen	PT	C0518015
Haemolytic anaemia	nitrogen	LLT	C0002878
Haemolytic anaemia	nitrogen	PT	C0002878
Haemorrhage	nitrogen	LLT	C0019080
Haemorrhage	nitrogen	PT	C0019080
Herpes zoster	nitrogen	LLT	C0019360
Herpes zoster	nitrogen	PT	C0019360
Hypersensitivity	nitrogen	LLT	C0020517
Hypersensitivity	nitrogen	PT	C0020517
Infection	nitrogen	LLT	C0009450
Infection	nitrogen	PT	C0009450
Jaundice	nitrogen	LLT	C0022346
Jaundice	nitrogen	PT	C0022346
Leukopenia	nitrogen	LLT	C0023530
Leukopenia	nitrogen	PT	C0023530
Lymphopenia	nitrogen	LLT	C0024312
Lymphopenia	nitrogen	PT	C0024312
Mediastinum neoplasm	nitrogen	LLT	C0025063
Mediastinum neoplasm	nitrogen	PT	C0025063
Menstruation delayed	nitrogen	LLT	C0240322
Menstruation delayed	nitrogen	PT	C0240322
Nausea	nitrogen	LLT	C0027497
Nausea	nitrogen	PT	C0027497
Oligomenorrhoea	nitrogen	LLT	C0028949
Oligomenorrhoea	nitrogen	PT	C0028949
Oliguria	nitrogen	LLT	C0028961
Oliguria	nitrogen	PT	C0028961
Pancytopenia	nitrogen	LLT	C0030312
Pancytopenia	nitrogen	PT	C0030312
Petechiae	nitrogen	LLT	C0031256
Petechiae	nitrogen	PT	C0031256
Platelet count normal	nitrogen	LLT	C0427564
Platelet count normal	nitrogen	PT	C0427564
Pruritus	nitrogen	LLT	C0033774
Pruritus	nitrogen	PT	C0033774
Rash	nitrogen	LLT	C0015230
Rash	nitrogen	PT	C0015230
Skin bacterial infection	nitrogen	LLT	C0162627
Skin bacterial infection	nitrogen	PT	C0162627
Skin cancer	nitrogen	PT	C0007114
Skin carcinoma	nitrogen	LLT	C0699893
Skin disorder	nitrogen	PT	C0037274
Skin hyperpigmentation	nitrogen	LLT	C0162834
Skin hyperpigmentation	nitrogen	PT	C0162834
Skin ulcer	nitrogen	LLT	C0037299
Skin ulcer	nitrogen	PT	C0037299
Superior vena cava syndrome	nitrogen	LLT	C0038833
Superior vena cava syndrome	nitrogen	PT	C0038833
Thrombocytopenia	nitrogen	LLT	C0040034
Thrombocytopenia	nitrogen	PT	C0040034

SOURCE Rendered pharma page rows FAQPage JSON-LD

Frequently Asked Questions

Short answers generated only from the same visible source-linked rows on this page.

What is Nitrogen used for in pharmaceutical contexts?

Nitrogen (CAS 7727-37-9) is rendered as a pharmaceutical compound from the matched source rows; no DailyMed product-name rows are present in this page query.

What are the known adverse events for Nitrogen?

Nitrogen has 558 DrugCentral/FAERS adverse event associations. Rendered reaction terms include Dyspnoea, Pulmonary arterial hypertension, Oxygen saturation decreased, Pulmonary hypertension, Right ventricular failure. Signal rows are source-linked records and should not be read as incidence rates or causality conclusions.

Is Nitrogen also used in cosmetics?

Yes. The ingredients table has a same-CAS cosmetic profile for NITROGEN with EU status "permitted".

What clinical phase is Nitrogen in?

Nitrogen is rendered with ChEMBL max phase 4 (approved).