Is NITROGEN safe in cosmetics?
NITROGEN has a safety rating of "GOOD" in our database. EU status: permitted. US status: allowed.
NITROGEN
Also known as: EINECS 231-783-9, MOL Nitrogen, UNII-N762921K75, N#N, N2 (+1 more)
NITROGEN (CAS 7727-37-9) is a cosmetic cosmetic ingredient functioning as Propellant. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 7727-37-9 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
NITROGEN is classified GHS Danger (H280, H304, H401, H281) in the chemicals database but is allowed in EU cosmetics.
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Propellant
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
molecular nitrogen
InChIKey
IJGRMHOSHXDMSA-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
allowed
US Notes
Allowed — GRAS for food contact; permitted in cosmetics as a propellant and inert atmosphere gas
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
GHS Hazard Classification
Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.
Routes of Exposure
The substance can be absorbed into the body by inhalation.
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Safety (2)
ICSC Safety Card
1198
Source: ILO-WHO International Chemical Safety Cards (ICSCs)
ICSC Safety Card
1199
Source: ILO-WHO International Chemical Safety Cards (ICSCs)
Regulatory (2)
JECFA Evaluation
NITROGEN | 1980 | NO ADI NECESSARY | TRS 653-JECFA 24/25 | NOT PREPARED
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
EU Food Improvement
Food additives
Source: EU Food Improvement Agents
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Antioxidant
Degradant/impurity
No specific technical function
Processing aids not otherwise specified
Propellants
non-motive (blowing agents)
Soil amendments
Regulatory List Membership (2)
EPA Safer Chemical Ingredients List (SCIL)
FDA Substances Added to Food (EAFUS)
Expert Verdict
Expert safety assessment and concern-level summary for NITROGEN.
Regulatory Flags
cosing-sourced
eu-permitted
needs-enrichment
epa_safer_alternative
fda_food_additive
Known Synonyms
EINECS 231-783-9
MOL Nitrogen
UNII-N762921K75
N#N
N2
Total Nitrogen (N)
Chemical Function
Propellants
non-motive (blowing agents)
Degradant/impurity
Regulatory Lists
active_ingredient; Europe; Pesticides
inert_ingredient; Pesticides
inert_ingredient; non_food_use; Pesticides
inert_ingredient; non_food_use; Pesticides
active_ingredient; Europe; Pesticides
agricultural; applied; fruits_and_vegetables
agricultural; applied; fruits_and_vegetables
agricultural; applied; fruits_and_vegetables
agricultural; applied; fruits_and_vegetables
agricultural; applied; fruits_and_vegetables
agricultural; applied; fruits_and_vegetables
agricultural; applied; fruits_and_vegetables
agricultural; applied; fruits_and_vegetables
agricultural; applied; fruits_and_vegetables
agricultural; applied; fruits_and_vegetables
agricultural; applied; fruits_and_vegetables
agricultural; applied; fruits_and_vegetables
agricultural; applied; fruits_and_vegetables
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
NITROGEN
ChEMBL ID
CHEMBL142438
Max Phase
4
Adverse Event Associations
558
Frequently Asked Questions
Is NITROGEN allowed in the EU?
NITROGEN EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does NITROGEN do in cosmetics?
NITROGEN functions as: Propellant. It is classified as a cosmetic ingredient in our database. CAS number: 7727-37-9.
Is NITROGEN used outside cosmetics?
NITROGEN also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does NITROGEN have different safety status in cosmetics vs industrial chemicals?
NITROGEN is classified GHS Danger (H280, H304, H401, H281) in the chemicals database but is allowed in EU cosmetics.
Compliance Tools
Check NITROGEN compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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