sccs_opinions
Max 2.0%
safe
Key concerns: sensitisation potential; impurity concerns
Opinion date: 27 March 2012
SCCS/1464/12
16 NOAEL rows
Safety conclusion
s are allowed for other uses than preservation., Soytrimonium chloride
Structured SCCS opinion summary generated from source-matched D1 rows for SCCS/1464/12.
Opinion Number
SCCS/1464/12
NOAEL Rows
16
Substances Covered
2
Substance(s) Covered
s are allowed for other uses than preservation.
Soytrimonium chloride
NOAEL Values Extracted from This Opinion
| Substance | Endpoint | Value | Study | Source |
|---|---|---|---|---|
|
s are allowed for other uses than preservation.
61790-41-8
|
NOAEL | 63 mg/kg | chronic |
Regulatory source
p.31
SCCS Opinion
|
|
s are allowed for other uses than preservation.
61790-41-8
|
NOAEL | 9.9 % |
developmental toxicity rat dermal |
SCCS Opinion
p.33
SCCS Opinion
|
|
s are allowed for other uses than preservation.
61790-41-8
|
NOAEL | 9.9 % |
developmental toxicity rat dermal |
SCCS Opinion
p.33
SCCS Opinion
|
|
s are allowed for other uses than preservation.
61790-41-8
|
NOAEL | 9.9 % |
developmental toxicity rat dermal |
SCCS Opinion
p.33
SCCS Opinion
|
|
s are allowed for other uses than preservation.
61790-41-8
|
NOAEL | 9.9 % |
developmental toxicity rat dermal |
SCCS Opinion
p.33
SCCS Opinion
|
|
s are allowed for other uses than preservation.
61790-41-8
|
developmental toxicity | 9.9 % |
developmental toxicity rat dermal |
Regulatory source
p.33
SCCS Opinion
|
|
s are allowed for other uses than preservation.
61790-41-8
|
developmental toxicity | 10 mg/kg bw/day |
developmental toxicity rat oral 12 months |
Regulatory source
p.39
SCCS Opinion
|
|
s are allowed for other uses than preservation.
61790-41-8
|
developmental toxicity | 125 mg/kg bw/d |
developmental toxicity rat dermal Developmental |
Regulatory source
p.39
SCCS Opinion
|
|
s are allowed for other uses than preservation.
61790-41-8
|
genotoxicity | 10 mg/kg bw/day |
genotoxicity chronic |
Regulatory source
p.31
SCCS Opinion
|
|
s are allowed for other uses than preservation.
61790-41-8
|
genotoxicity | 10 mg/kg bw/day |
genotoxicity chronic |
Regulatory source
p.31
SCCS Opinion
|
|
s are allowed for other uses than preservation.
61790-41-8
|
genotoxicity | 10 mg/kg bw/day |
genotoxicity chronic |
Regulatory source
p.31
SCCS Opinion
|
|
s are allowed for other uses than preservation.
61790-41-8
|
irritation | 10 mg/kg bw/day | irritation |
Regulatory source
p.30
SCCS Opinion
|
|
s are allowed for other uses than preservation.
61790-41-8
|
irritation | 24 % |
irritation rabbit dermal 28-day |
Regulatory source
p.29
SCCS Opinion
|
|
s are allowed for other uses than preservation.
61790-41-8
|
repeated dose toxicity | 10 mg/kg bw/day |
repeated dose toxicity oral 28-day |
Regulatory source
p.30
SCCS Opinion
|
|
s are allowed for other uses than preservation.
61790-41-8
|
repeated dose toxicity | 10 mg/kg bw/day |
repeated dose toxicity rat oral chronic |
Regulatory source
p.39
SCCS Opinion
|
|
s are allowed for other uses than preservation.
61790-41-8
|
reproductive toxicity | 0.1 |
reproductive toxicity rabbit dermal |
Regulatory source
p.32
SCCS Opinion
|