SCCS/1601/18 4 NOAEL rows Safety conclusion

codes .............................................. 8, Salicylic acid - Submission I

Structured SCCS opinion summary generated from source-matched D1 rows for SCCS/1601/18.

Opinion Number

SCCS/1601/18

NOAEL Rows

Substances Covered

Substance(s) Covered

codes .............................................. 8 Salicylic acid - Submission I

Substance	Endpoint	Value	Study	Source
codes .............................................. 8 118-56-9	NOAEL	75 mg/kg bw/d	NOAEL study human	SCCS Opinion p.47
codes .............................................. 8 118-56-9	NOAEL	75 mg/kg bw/d	NOAEL study human	SCCS Opinion p.47
codes .............................................. 8 118-56-9	NOAEL	75 mg/kg bw/d	NOAEL study human	SCCS Opinion p.47
codes .............................................. 8 118-56-9	NOAEL	75 mg/kg bw/d	NOAEL study human	SCCS Opinion p.47

sccs_opinions Max 0.5% preservative; 2% other products; 3% rinse-off hair products; 1.5% face products

safe with restrictions

Key concerns: Endocrine disrupting properties not yet evaluated in this submission; 60% dermal penetration value used

Opinion date: 21 December 2018