EFSA toxicology reference values
3-Methylindole
SOURCE
efsa openfoodtox 3 0 export repository
3-Methylindole (CAS 83-34-1). Cannabis testing data across 0 states. Action levels when present, testing requirements, compliance status.
3-Methylindole is a cannabis analyte contaminant represented in the cannabis public dataset.
CAS 83-34-1
Cannabis Analyte
Substance Identity
Analyte identity and classification used for this cannabis substance page.
SOURCE
efsa substances
Analyte name
3-Methylindole
CAS number
83-34-1
Contaminant class
Cannabis Analyte
Contaminant Class Badge
Color-coded cannabis class signal for scanning pesticide, metal, solvent, mycotoxin, and potency pages.
SOURCE
State Cannabis Regulations
Cannabis Analyte
Cannabis contaminant class used to group state testing rows.
Dataset Snapshot
Compact public-data summary for page quality, state coverage, lab rows, and potency sample groups.
SOURCE
cannabis page data
Quality score
2
thin
Jurisdictions
0
No state rows
Lab/analyte rows
0
0 failed (-)
Potency samples
0
83-34-1
EFSA Substance Identity
EFSA substance identity rows matched by chemical name or CAS.
SOURCE
efsa openfoodtox 3 0 export repository
3-Methylindole
CAS 83-34-1 / mono-constituent substance
C9H9N / 5 dossier(s)
EFSA Reference Values
Reference values from efsa_reference_values_v2 for toxicology and food-safety context.
SOURCE
efsa openfoodtox 3 0 export repository
| Descriptor | Value | Population | Endpoint | Body |
|---|---|---|---|---|
| MSI/FC | 1 mg/kg | other: | - | - |
| MSI/FC | 1 mg/kg | other: | - | - |
| MSI/FC | 1.5 mg/kg | other: | - | - |
| MSI/FC | 1.5 mg/kg | other: | - | - |
| MSI/FC | 1.5 mg/kg | salmon | - | - |
| TTC Cramer Class II | 9 µg/kg bw/day | consumers | - | - |
| TTC Cramer Class I | 30 µg/kg bw/day | consumers | - | - |
| TTC Cramer Class I | 30 µg/kg bw/day | consumers | - | - |
| TTC Cramer Class I | 30 µg/kg bw/day | consumers | - | - |
| margin of safety | - | consumers | - | - |
EFSA Study Results
Endpoint-level study rows from efsa_study_results matched to this substance.
SOURCE
efsa openfoodtox 3 0 export repository
| Endpoint | Species | Route | Effect | Assessment |
|---|---|---|---|---|
| appearance / physical state / colour | - | - | - | experimental study |
| solubility in organic solvents / fat solubility | - | - | - | experimental study |
| melting point/freezing point | - | - | - | experimental study |
| refractive index | - | - | - | experimental study |
| other: | - | - | - | experimental study |
| water solubility | - | - | - | experimental study |
| Carcinogenicity_EU_PPP | - | - | - | The Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids of the European Food Safety Authority was requested to consider evaluations of flavouring substances assessed since 2000 by the Joint FAO/WHO Expert Committee on Food Additives (JECFA), and to decide whether further evaluation is necessary, as laid down in Commission Regulation (EC) No 1565/2000. The present consideration concerns a group of 22 pyridine, pyrrole and quinoline derivatives evaluated by JECFA (63 rd meeting). The revision of this consideration is made since additional toxicity data have become available for 1-furfurylpyrrole [FL-no: 13.134]. The data are intended to cover the re-evaluation of this substance and 2-acetyl-1-ethylpyrrole [FL-no: 14.045] and 2-acetyl-1-methylpyrrole [FL-no: 14.046]. |
| Carcinogenicity_EU_PPP | - | - | - | The Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids of the European Food Safety Authority was requested to consider evaluations of flavouring substances assessed since 2000 by the Joint FAO/WHO Expert Committee on Food Additives (the JECFA), and to decide whether further evaluation is necessary, as laid down in Commission Regulation (EC) No 1565/2000. The present consideration concerns a group of 22 pyridine, pyrrole and quinoline derivatives evaluated by the JECFA (63rd meeting). This revision is made due to new 90-day studies provided for isoquinoline [FL-no: 14.001], pyrrole [FL-no: 14.041] and 2-acetylpyrrole [FL-no: 14.047]. The data on 2-acetylpyrrole should also cover 2-propionylpyrrole [FL-no: 14.068]. Further, additional genotoxicity data on 6-methylquinoline [FL-no: 14.042] have also become available. The present consideration therefore concerns these additional data and will be considered in relation to the European Food safety Authority (EFSA) evaluation of 24 pyridine, pyrrole, indole and quinoline derivatives evaluated in the Flavouring Group Evaluation 24, Revision 2 (FGE.24Rev2). |
| Carcinogenicity_EU_PPP | - | - | - | The Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids of the EFSA was requested to consider evaluations of flavouring substances assessed since 2000 by the Joint FAO/WHO Expert Committee on Food Additives (JECFA) and to decide whether further evaluation is necessary, as laid down in Commission Regulation (EC) No 1565/2000. The present consideration concerns a group of 22 pyridine, pyrrole and quinoline derivatives evaluated by JECFA (63rd meeting). The revision of this consideration is made since additional genotoxicity data have become available for 6-methylquinoline [FL-no: 14.042]. |
| Carcinogenicity_EU_PPP | - | - | - | Following a request from the European Commission, the EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of nine compounds belonging to chemical group 28 (pyridine, pyrrole and quinoline derivatives). They are currently authorised as flavours in food. |
| Carcinogenicity_EU_PPP | - | - | - | The Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food (the Panel) is asked to advise the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular the Scientific Panel is requested to consider the Joint FAO/WHO Expert Committee on Food Additives (the JECFA) evaluations of flavouring substances assessed since 2000, and to decide whether no further evaluation is necessary, as laid down in Commission Regulation (EC) No 1565/2000. These flavouring substances are listed in the Register, which was adopted by Commission Decision 1999/217/EC, and its consecutive amendments. The present consideration concerns 22 pyridine, pyrrole and quinoline derivatives evaluated by the JECFA (63rd meeting) and will be considered in relation to the European Food Safety Authority (EFSA) evaluation of pyridine, pyrrole, indole and quinoline derivatives evaluated in the Flavouring Group Evaluation 24, Revision 1 (FGE.24Rev1). The Panel concluded that the 22 substances in the JECFA flavouring group of pyridine, pyrrole and quinoline derivatives are structurally related to the group of pyridine, pyrrole, indole and quinolone derivatives evaluated by EFSA in FGE.24Rev1. |
| Genetic Toxicity | - | - | - | The Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids of the European Food Safety Authority was requested to consider evaluations of flavouring substances assessed since 2000 by the Joint FAO/WHO Expert Committee on Food Additives (the JECFA), and to decide whether further evaluation is necessary, as laid down in Commission Regulation (EC) No 1565/2000. The present consideration concerns a group of 22 pyridine, pyrrole and quinoline derivatives evaluated by the JECFA (63rd meeting). This revision is made due to new 90-day studies provided for isoquinoline [FL-no: 14.001], pyrrole [FL-no: 14.041] and 2-acetylpyrrole [FL-no: 14.047]. The data on 2-acetylpyrrole should also cover 2-propionylpyrrole [FL-no: 14.068]. Further, additional genotoxicity data on 6-methylquinoline [FL-no: 14.042] have also become available. The present consideration therefore concerns these additional data and will be considered in relation to the European Food safety Authority (EFSA) evaluation of 24 pyridine, pyrrole, indole and quinoline derivatives evaluated in the Flavouring Group Evaluation 24, Revision 2 (FGE.24Rev2). |
Cross-Reference to Chemicals / Cosmetics / Food
Internal cross-vertical links connecting cannabis rows to chemical, cosmetics, and EFSA food/toxicology context.
SOURCE
core public cross-reference
Frequently Asked Questions
FAQ answers are generated from the same fetched cannabis, EFSA, cosmetics, and chemical rows rendered above.
SOURCE
page FAQ dataset
What is the regulatory limit for 3-Methylindole in cannabis?
3-Methylindole does not have a numeric cannabis_contaminant_tests range in the fetched page data. The current page query does not expose a separate action-limit column.
Which states test for 3-Methylindole?
3-Methylindole does not have state-level cannabis testing rows in the fetched page data.
What are the EFSA reference values for 3-Methylindole?
3-Methylindole has 10 EFSA OpenFoodTox reference value rows in the cannabis database, including MSI/FC, TTC Cramer Class II, TTC Cramer Class I, margin of safety.
Is 3-Methylindole also regulated in cosmetics or food?
3-Methylindole has a cosmetics ingredient cross-reference with EU status permitted. EFSA food/toxicology context is available on this page.