Regulatory Status
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Safety Data
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Expert Verdict
Pulmonary toxicant in animal models (3-methylindole causes lung injury via CYP-mediated bioactivation). IFRA concentration limits apply. Known odorant in feces — potential consumer perception issues. Requires strict concentration control
Regulatory Flags
Frequently Asked Questions
Is Skatole safe in cosmetics?
Pulmonary toxicant in animal models (3-methylindole causes lung injury via CYP-mediated bioactivation). IFRA concentration limits apply. Known odorant in feces — potential consumer perception issues. Requires strict concentration control The EU classifies Skatole as "permitted". Safety rating: MODERATE.
Is Skatole allowed in the EU?
Skatole EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Skatole do in cosmetics?
Skatole functions as: Fragrance (animalic/fecal/floral note in trace amounts). It is classified as a cosmetic ingredient in our database. CAS number: 83-34-1.
What is the Margin of Safety for Skatole?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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