EFSA toxicology reference values
piperine
piperine (CAS 94-62-2). Cannabis testing data across 0 states. Action levels when present, testing requirements, compliance status.
piperine is a cannabis analyte contaminant represented in the cannabis public dataset.
Substance Identity
Analyte identity and classification used for this cannabis substance page.
Contaminant Class Badge
Color-coded cannabis class signal for scanning pesticide, metal, solvent, mycotoxin, and potency pages.
Dataset Snapshot
Compact public-data summary for page quality, state coverage, lab rows, and potency sample groups.
EFSA Substance Identity
EFSA substance identity rows matched by chemical name or CAS.
EFSA Reference Values
Reference values from efsa_reference_values_v2 for toxicology and food-safety context.
| Descriptor | Value | Population | Endpoint | Body |
|---|---|---|---|---|
| TTC Cramer Class III | 1.5 µg/kg bw/day | consumers | - | - |
| TTC Cramer Class III | 1.5 µg/kg bw/day | consumers | - | - |
| TTC Cramer Class III | 1.5 µg/kg bw/day | consumers | - | - |
| margin of safety | >48,000 other: | consumers | 85165b4b-d543-4cfa-b43f-717ab28cda8d | - |
| Incomplete dataset | - | consumers | - | - |
| Incomplete dataset | - | consumers | - | - |
EFSA Study Results
Endpoint-level study rows from efsa_study_results matched to this substance.
| Endpoint | Species | Route | Effect | Assessment |
|---|---|---|---|---|
| sub-chronic toxicity: oral | rat | oral: feed | 5 other: | - |
| Carcinogenicity_EU_PPP | - | - | - | Following a request from the European Commission, the EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF Panel) was asked to deliver scientific advice to the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the CEF Panel was requested to consider the Joint FAO/WHO Expert Committee on Food Additives (JECFA) evaluations of flavouring substances assessed since 2000, and to decide whether no further evaluation is necessary, as laid down in Commission Regulation (EC) No 1565/2000. These flavouring substances are listed in theRegister, which was adopted by Commission Decision 1999/217/EC and its consecutive amendments. The present revision of FGE.86Rev1 is due to the submission of the requested toxicity data for [FLno: 14.003 and 16.091]. |
| Carcinogenicity_EU_PPP | - | - | - | The European Food Safety Authority (EFSA) asked the Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (the Panel) to provide scientific advice to the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Panel was requested to consider the Joint FAO/WHO Expert Committee on Food Additives (the JECFA) evaluations of flavouring substances assessed since 2000, and to decide whether no further evaluation is necessary, as laid down in Commission Regulation (EC) No 1565/2000. These flavouring substances are listed in the Register, which was adopted by Commission Decision 1999/217/EC and its consecutive amendments. The present consideration concerns 34 aliphatic and aromatic amines and amides evaluated by the JECFA (65th meeting). The Panel concluded that no corresponding FGE is available. |
| Carcinogenicity_EU_PPP | - | - | - | The Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food (the Panel) is asked to advise the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular the Scientific Panel is requested to consider the Joint FAO/WHO Expert Committee on Food Additives (the JECFA) evaluations of flavouring substances assessed since 2000, and to decide whether no further evaluation is necessary, as laid down in Commission Regulation (EC) No 1565/2000. These flavouring substances are listed in the Register, which was adopted by Commission Decision 1999/217/EC, and its consecutive amendments. The present consideration concerns 35 aliphatic and aromatic amines and amides evaluated by the JECFA (65th meeting). The Panel concluded that no corresponding FGE is available. |
| Genetic Toxicity | - | - | - | The Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food (the Panel) is asked to advise the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular the Scientific Panel is requested to consider the Joint FAO/WHO Expert Committee on Food Additives (the JECFA) evaluations of flavouring substances assessed since 2000, and to decide whether no further evaluation is necessary, as laid down in Commission Regulation (EC) No 1565/2000. These flavouring substances are listed in the Register, which was adopted by Commission Decision 1999/217/EC, and its consecutive amendments. The present consideration concerns 35 aliphatic and aromatic amines and amides evaluated by the JECFA (65th meeting). The Panel concluded that no corresponding FGE is available. |
| Genetic Toxicity | - | - | - | Following a request from the European Commission, the EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF Panel) was asked to deliver scientific advice to the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the CEF Panel was requested to consider the Joint FAO/WHO Expert Committee on Food Additives (JECFA) evaluations of flavouring substances assessed since 2000, and to decide whether no further evaluation is necessary, as laid down in Commission Regulation (EC) No 1565/2000. These flavouring substances are listed in theRegister, which was adopted by Commission Decision 1999/217/EC and its consecutive amendments. The present revision of FGE.86Rev1 is due to the submission of the requested toxicity data for [FLno: 14.003 and 16.091]. |
| Genetic Toxicity | - | - | - | The European Food Safety Authority (EFSA) asked the Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (the Panel) to provide scientific advice to the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Panel was requested to consider the Joint FAO/WHO Expert Committee on Food Additives (the JECFA) evaluations of flavouring substances assessed since 2000, and to decide whether no further evaluation is necessary, as laid down in Commission Regulation (EC) No 1565/2000. These flavouring substances are listed in the Register, which was adopted by Commission Decision 1999/217/EC and its consecutive amendments. The present consideration concerns 34 aliphatic and aromatic amines and amides evaluated by the JECFA (65th meeting). The Panel concluded that no corresponding FGE is available. |
Cross-Reference to Chemicals / Cosmetics / Food
Internal cross-vertical links connecting cannabis rows to chemical, cosmetics, and EFSA food/toxicology context.
Frequently Asked Questions
FAQ answers are generated from the same fetched cannabis, EFSA, cosmetics, and chemical rows rendered above.
What is the regulatory limit for piperine in cannabis?
piperine does not have a numeric cannabis_contaminant_tests range in the fetched page data. The current page query does not expose a separate action-limit column.
Which states test for piperine?
piperine does not have state-level cannabis testing rows in the fetched page data.
What are the EFSA reference values for piperine?
piperine has 6 EFSA OpenFoodTox reference value rows in the cannabis database, including TTC Cramer Class III, margin of safety, Incomplete dataset.
Is piperine also regulated in cosmetics or food?
piperine has a cosmetics ingredient cross-reference with EU status permitted. EFSA food/toxicology context is available on this page.