What is the NOAEL for Geranyl acetate?
Geranyl acetate has 20 NOAEL studies in the database. The lowest reported value is 0 % via Dermal in Human. Source: NTP ICE skin sensitization.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Geranyl acetate
Also known as: trans-Geraniol acetate, 4-02-00-00204, Acetic acid, geraniol ester, BRN 1722815, 3,7-Dimethyl-2-trans, 6-octadienyl acetate (+13 more)
CAS 105-87-3
Geranyl acetate (CAS 105-87-3) is a chemical substance. Key regulatory status: REACH registered, 8 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
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NOAEL studies
NOAEL studies
20
SOURCE
Chemical inventory jurisdictions
Regulatory lists
8
SOURCE
EU CLP Annex VI
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
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DSSTox identifiers
23 fields
Name
Geranyl acetate
CAS Number
105-87-3
Molecular Formula
C12H20O2
InChI Key
HIGQPQRQIQDZMP-DHZHZOJOSA-N
Monoisotopic Mass
196.14633
Synonyms
trans-Geraniol acetate4-02-00-00204Acetic acid, geraniol esterBRN 17228153,7-Dimethyl-2-trans, 6-octadienyl acetate2,6-Dimethyl-2,6-octadiene-8-yl acetatetrans-3,7-Dimethyl-2,6-octadien-1-ol, acetatetrans-2,6-Dimethyl-2,6-octadien-8-yl ethanoate3,7-Dimethyl-2,6-octadien-1-yl ethanoate, trans-EINECS 203-341-5FEMA No. 2509FEMA Number 2509
Functional Uses
Industrial and product-use categories associated with this substance.
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EPA CPDat
60 records
FragranceHumectantNo specific technical functionFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
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EPA CPDat
8 records
| List | Keyword | Source |
|---|---|---|
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
| detected; Europe; Personal care - sexual wellness | Danish Environmental Protection Agency | Danish EPA |
| detected; Europe; Personal care - sexual wellness | Danish Environmental Protection Agency | Danish EPA |
| Australia; Food and drug - smoking-related products | New Zealand ESR | CPCat |
| IFRA Transparency | IFRA | IFRA |
| Europe | European Commission | Fl@vis |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| consumer_product | P&G | Proctor & Gamble |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
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NOAEL studies
Showing 20 of 20 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 823 | uL/min/10^6 cells | Clint | - | Human | NTP ICE adme parameters |
| =62.59 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB GESTIS DNEL |
| 3W81YG7P9R | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 0.192 | fraction | Fu | - | Human | NTP ICE adme parameters |
| 0 | % | Incidence of positive responses | Dermal | Human | NTP ICE skin sensitization |
| 2483 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP ICE skin sensitization |
| =6330 | mg/kg bw | LD50 | oral | Rat | NTP ICE acute oral |
| =2000 | mg/kg bw/day | LOEL | oral | Mouse | ToxValDB ECOTOX |
| 0 | unitless | Model Score | - | - | NTP ICE endocrine |
| =345 | mg/kg bw/day | NOAEL | oral | Rat | EFSA |
| =345 | mg/kg bw/day | NOAEL | oral: feed | Rat | EFSA |
| 1000 | mg/kg bw/day | NOAEL | oral | rat | COSMOS DB |
| =1000 | mg/kg bw/day | NOAEL | oral | Mouse | ECHA |
| 2000 | mg/kg bw/day | NOAEL | oral | rat | COSMOS DB |
| =2000 | mg/kg bw/day | NOAEL | oral | Rat | ECHA |
| 4000 | mg/kg bw/day | NOAEL | oral | rat | COSMOS DB |
| =2000 | mg/kg bw/day | NOEL | oral | Rat | ToxValDB ECOTOX |
| 2 | unitless | Relative reliability score | Dermal | Human | NTP ICE skin sensitization |
| 1000 | mg/kg bw/day | Top dose | Gavage | Mouse | NTP ICE cancer |
| 2000 | mg/kg bw/day | Top dose | Gavage | Rat | NTP ICE cancer |
Showing 20 of 20 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
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ECHA
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Geranyl acetate | 203-341-5 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
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AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
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CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
aroma_chemical
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
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ChEMBL / DailyMed
GERANYL ACETATE
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
3
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
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EFSA
1 records
ADI: 0-0.5 mg/kg bw (1979) mg/kg bw
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
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Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Geranyl acetate?
Geranyl acetate appears on 7 regulatory/inventory lists including inert_ingredient; non_food_use; Pesticides, detected; Europe; Personal care - sexual wellness, Australia; Food and drug - smoking-related products, and 4 more. Source: EPA CPDat.
Is Geranyl acetate used in cosmetics?
Yes, Geranyl acetate is also indexed as a cosmetic ingredient under the name Geranyl Acetate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Geranyl acetate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is Geranyl acetate used outside industrial chemicals?
Geranyl acetate also appears in cosmetics, pharmaceutical, food safety, cannabis databases.