Is Geranyl Acetate safe in cosmetics?
Geranyl Acetate has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
GOOD
Cosmetic Ingredient
Geranyl Acetate
Also known as: trans-Geraniol acetate, 4-02-00-00204, Acetic acid, geraniol ester, BRN 1722815, 3,7-Dimethyl-2-trans, 6-octadienyl acetate (+13 more)
INCI: GERANYL ACETATE
Geranyl Acetate (CAS 105-87-3) is a cosmetic cosmetic ingredient functioning as Fragrance. NOAEL 1000 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety, pharmaceutical, and food safety data.
Function
Fragrance
Editorial assessment
GOOD
Preliminary editorial note — not a computed safety verdict.
Chemistry & Identifiers
IUPAC Name
[(2E)-3,7-dimethylocta-2,6-dienyl] acetate
InChIKey
HIGQPQRQIQDZMP-DHZHZOJOSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
FEMA GRAS No. 2509; no specific FDA restrictions
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Geranyl Acetate.
Calculate MoS for your specific formulation with the MoS Calculator.
Pre-Calculated Safety Assessment
Pre-calculated NOAEL → SED → MoS audit trail for Geranyl Acetate across SCCS product categories, with measured dermal absorption where available.
HRIPT Human Patch Test Studies
2 human repeat insult patch tests aggregated from dermatological literature.
| Test Type | N | Sensitized | Dose µg/cm² | NESIL µg/cm² | Potency |
|---|---|---|---|---|---|
| HRIPT | 111 | 0 | 5019 | 5019 | non-sensitizer |
| HMT | - | 0 | 2482.76 | - | - |
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
100 - 1,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Safety (3)
Carcinogen Classification
Geranyl acetate | TR-252: Carcinogenesis Studies of Food Grade Geranyl Acetate (71% Geranyl Acetate, 29% Citronellyl Acetate) (CASRN 105-87-3) in F344/N Rats and B6C3F1 Mice (Gavage Study) (1987 ) | 09/22/82 | No Evidence | No Evidence | No Evidence | No Evidence | Under the conditions of these studies, geranyl acetate was not carcinogenic for F344/N rats or B6C3F1 mice of either sex;…
Source: NTP Technical Reports
Endocrine Disruptors
Potential endocrine disrupting compound
Source: NORMAN Suspect List Exchange
Skin Eye Respiratory Irritation
In human patch test, geraniol @ 32% concn was severely irritating & geranyl acetate mildly irritating.
Source: Hazardous Substances Data Bank (HSDB)
Regulatory (2)
JECFA Number
58
Source: WHO/JECFA
JECFA Evaluation
GERANYL ACETATE | 1997 | 0-0.5 mg/kg bw (1979) | No safety concern at current levels of intake when used as a flavouring agent. The 1979 group ADI of 0-0.5 mg/kg bw for citral, geranyl acetate, citronellol, linalool, and linalyl acetate, expressed as citral, was maintained at the fifty-first (TRS 891/90, 1998) and sixty-first (TRS for JECFA 61 in press) meetings. | TRS 884-JECFA 49/64 | FAS…
Source: WHO/JECFA
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Humectant
No specific technical function
Regulatory List Membership (3)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Consumer Product Chemical
Editorial summary
Preliminary editorial summary for Geranyl Acetate — not a computed safety verdict. See the sourced toxicological data above.
Regulatory Flags
ifra_fragrance
fda_food_additive
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to Geranyl Acetate by CAS number or substance name.
Studies
9
Lowest NOAEL
100 mg/kg bw/day
Highest NOAEL
1000 mg/kg bw/day
ECHA
Known Synonyms
trans-Geraniol acetate
4-02-00-00204
Acetic acid, geraniol ester
BRN 1722815
3,7-Dimethyl-2-trans, 6-octadienyl acetate
2,6-Dimethyl-2,6-octadiene-8-yl acetate
trans-3,7-Dimethyl-2,6-octadien-1-ol, acetate
trans-2,6-Dimethyl-2,6-octadien-8-yl ethanoate
3,7-Dimethyl-2,6-octadien-1-yl ethanoate, trans-
EINECS 203-341-5
FEMA No. 2509
FEMA Number 2509
Geranyl acetate A
NCI-C54728
2,6-Octadien-1-ol, 3,7-dimethyl-, acetate, trans-
2,6-Octadien-1-ol, 3,7-dimethyl-, acetate,(E)-
UNII-3W81YG7P9R
(2E)-3,7-dimethylocta-2,6-dien-1-yl acetate
Chemical Function
Fragrance
Regulatory Lists
inert_ingredient; non_food_use; Pesticides
detected; Europe; Personal care - sexual wellness
detected; Europe; Personal care - sexual wellness
Australia; Food and drug - smoking-related products
IFRA Transparency
Europe
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
consumer_product
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical and food safety data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
GERANYL ACETATE
ChEMBL ID
CHEMBL1369384
SOURCE
EFSA / FDA GRAS
food_additives
Food Safety Data
Same-CAS food additive or FDA GRAS records from the core public database.
Food Name
GERANYL ACETATE
ADI
0-0.5 mg/kg bw (1979) mg/kg bw
Food Category
flavoring
Frequently Asked Questions
Is Geranyl Acetate allowed in the EU?
Geranyl Acetate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Geranyl Acetate do in cosmetics?
Geranyl Acetate functions as: Fragrance. It is classified as a cosmetic ingredient in our database. CAS number: 105-87-3.
Is Geranyl Acetate used outside cosmetics?
Geranyl Acetate also appears in industrial chemical safety, pharmaceutical, and food safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Geranyl Acetate compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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