NOAEL Data Cosmetic Ingredient

8'-Apo-beta, psi-carotenoid acid, ethyl ester

Also known as: Food orange 7

CAS 1109-11-1

8'-Apo-beta, psi-carotenoid acid, ethyl ester (CAS 1109-11-1) is a chemical substance. Key regulatory status: cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.

View cosmetic safety profile for CI 40825 (Ethyl Ester of 8'-Apo-Beta-Carotenoic Acid) →

SOURCE noael studies public

NOAEL studies

SOURCE chemical inventory jurisdictions

Regulatory lists

SOURCE eu clp annex vi

GHS signal

Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 7 fields

Name

8'-Apo-beta, psi-carotenoid acid, ethyl ester

CAS Number

1109-11-1

DTXSID

DTXSID901015586

Molecular Formula

C32H44O2

InChI Key

GIRXTOSJOKKBHO-BQTUIHPCSA-N

Monoisotopic Mass

460.334131

Synonyms

Food orange 7

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 1 records

Dye

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 5 of 5 studies

Value	Unit	Endpoint	Route	Species	Source
=0.015	mg/kg bw/day	ADI	-	Consumers	EFSA_OpenFoodTox_EFSA_ReferenceValues.xlsx
=0.015	mg/kg bw/day	ADI	-	Consumers	EFSA_OpenFoodTox_EFSA_ReferenceValues.xlsx
=80	mg/kg bw/day	LEL	oral	Chicken	ToxValDB_EFSA
=3	mg/kg bw/day	NOAEL	oral	Rat	ToxValDB_EFSA
=3	mg/kg bw/day	NOAEL	-	Rat	EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx

Showing 5 of 5 studies

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records

Inventory Status

listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB

EU Status

permitted

Max

Listed in Annex IV of EU Cosmetics Regulation (EC) No. 1223/2009 (Entry IV/57). Permitted as a colorant in all cosmetic products without a specified maximum concentration. Purity criteria must comply with Commission Directive 95/45/EC as applicable to E160f.

Food Safety Data

Same-CAS food additive, ADI, and GRAS records where available.

SOURCE EFSA / FDA GRAS 1 records

E160f — 1 food-safety record found.

View full food safety profile →

Cannabis Data

Same-CAS cannabis compliance and lab records where available.

SOURCE Cannabis regulatory / lab data efsa substances

1 cannabis record found in efsa substances.

View full cannabis profile →

Frequently Asked Questions

What is the NOAEL for 8'-Apo-beta, psi-carotenoid acid, ethyl ester?

8'-Apo-beta, psi-carotenoid acid, ethyl ester has 5 NOAEL studies in the database. The lowest reported value is 0.015 mg/kg bw/day in Consumers. Source: EFSA_OpenFoodTox_EFSA_ReferenceValues.xlsx.

Is 8'-Apo-beta, psi-carotenoid acid, ethyl ester used in cosmetics?

Yes, 8'-Apo-beta, psi-carotenoid acid, ethyl ester is also indexed as a cosmetic ingredient under the name CI 40825 (Ethyl Ester of 8'-Apo-Beta-Carotenoic Acid). View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for 8'-Apo-beta, psi-carotenoid acid, ethyl ester come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.

Is 8'-Apo-beta, psi-carotenoid acid, ethyl ester used outside industrial chemicals?

8'-Apo-beta, psi-carotenoid acid, ethyl ester also appears in cosmetics, food safety, cannabis databases.