Good Cosmetic Ingredient

CI 40825 (Ethyl Ester of 8'-Apo-Beta-Carotenoic Acid)

INCI: CI 40825

CAS Number

1109-11-1

Function

Colorant. Synthetic carotenoid colorant (Ethyl 8'-Apo-Beta-Caroten-8'-oate, also known as Beta-Apo-8'-Carotenic Acid Ethyl Ester and E160f). Imparts orange-to-red coloration to cosmetic products. A synthetic ester of the carotenoid acid derived from beta-carotene cleavage. Structurally related to apocarotenal (CI 40820) and beta-carotene (CI 40800). Used as a colorant in all cosmetic product types permitted under EU Annex IV.

Safety Rating

GOOD

Regulatory Status

🇪🇺 EU Status permitted

EU Max Conc. Listed in Annex IV of EU Cosmetics Regulation (EC) No. 1223/2009 (Entry IV/57). Permitted as a colorant in all cosmetic products without a specified maximum concentration. Purity criteria must comply with Commission Directive 95/45/EC as applicable to E160f.

🇺🇸 US Status prohibited

US Notes Not listed as an FDA-certified or exempt color additive for cosmetics under 21 CFR Parts 73, 74, or 82. CI 40825 (beta-apo-8'-carotenic acid ethyl ester / E160f) does not appear on the FDA Color Additives Permitted for Use in Cosmetics list. Regulatory status for US cosmetic use is not established; formulators must confirm permissibility before US market distribution.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)

not established

Dermal Absorption

low

Sensitization

low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

⚠️

Concern Level: Low

Regulatory Flags

eu-annex-iv not-fda-listed all-cosmetics-eu carotenoid-ester food-additive-e160f no-concentration-limit-eu us-regulatory-gap purity-criteria-required synthetic-carotenoid

Frequently Asked Questions

Is CI 40825 (Ethyl Ester of 8'-Apo-Beta-Carotenoic Acid) safe in cosmetics?

CI 40825 is a synthetic carotenoid ester colorant (Ethyl 8'-Apo-Beta-Caroten-8'-oate / E160f) permitted in all EU cosmetic products under Annex IV Entry IV/57, but not authorized for US cosmetics under FDA regulations. The EU classifies CI 40825 (Ethyl Ester of 8'-Apo-Beta-Carotenoic Acid) as "permitted". Safety rating: GOOD.

Is CI 40825 (Ethyl Ester of 8'-Apo-Beta-Carotenoic Acid) allowed in the EU?

CI 40825 (Ethyl Ester of 8'-Apo-Beta-Carotenoic Acid) EU regulatory status: permitted. Maximum allowed concentration: Listed in Annex IV of EU Cosmetics Regulation (EC) No. 1223/2009 (Entry IV/57). Permitted as a colorant in all cosmetic products without a specified maximum concentration. Purity criteria must comply with Commission Directive 95/45/EC as applicable to E160f.. This is based on EU Regulation 1223/2009 and its amendments.

What does CI 40825 (Ethyl Ester of 8'-Apo-Beta-Carotenoic Acid) do in cosmetics?

CI 40825 (Ethyl Ester of 8'-Apo-Beta-Carotenoic Acid) functions as: Colorant. Synthetic carotenoid colorant (Ethyl 8'-Apo-Beta-Caroten-8'-oate, also known as Beta-Apo-8'-Carotenic Acid Ethyl Ester and E160f). Imparts orange-to-red coloration to cosmetic products. A synthetic ester of the carotenoid acid derived from beta-carotene cleavage. Structurally related to apocarotenal (CI 40820) and beta-carotene (CI 40800). Used as a colorant in all cosmetic product types permitted under EU Annex IV.. It is classified as a cosmetic ingredient in our database. CAS number: 1109-11-1.

What is the Margin of Safety for CI 40825 (Ethyl Ester of 8'-Apo-Beta-Carotenoic Acid)?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check CI 40825 (Ethyl Ester of 8'-Apo-Beta-Carotenoic Acid) compliance across multiple jurisdictions:

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82 Allergen Checker

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Substance Compliance

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MoS Calculator

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Heavy Metal Limits

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