What is the GHS hazard classification for Hydrogen?
Hydrogen (CAS 1333-74-0) is classified under EU CLP Annex VI as Flam. Gas 1; Press. Gas with signal word Danger. Hazard statements: H220. Source: EU CLP Annex VI (ECHA).
Danger
GHS02GHS04
NOAEL Data
Cosmetic Ingredient
Hydrogen
Also known as: Dihydrogen, Hydrogen molecule, Mol. hydrogen, Molecular hydrogen, Orthohydrogen (+13 more)
CAS 1333-74-0
Hydrogen (CAS 1333-74-0) is a chemical substance with GHS signal word Danger; key hazard signal: H220. Key regulatory status: 4 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from ECHA CLP, EPA ToxValDB, EPA CPDat, AICIS, ILO ICSC.
Cross-Vertical Regulatory Divergence
Hydrogen is classified GHS Danger (H220) in the chemicals database but is allowed in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: eu_clp_annex_vi.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
5
SOURCE
chemical inventory jurisdictions
Regulatory lists
4
SOURCE
eu clp annex vi
GHS signal
Danger
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
24 fields
Name
Hydrogen
CAS Number
1333-74-0
DTXSID
DTXSID9029643
Molecular Formula
H2
InChI Key
UFHFLCQGNIYNRP-UHFFFAOYSA-N
Monoisotopic Mass
2.01565
Synonyms
DihydrogenHydrogen moleculeMol. hydrogenMolecular hydrogenOrthohydrogenParahydrogenHydrogen gasHydrogen elementHydrogen (H2)EINECS 215-605-7Hydrogen atomsUNII-7YNJ3PO35Z
GHS / CLP Classification
EU harmonized hazard classification, hazard statements, pictograms, and signal word.
SOURCE
EU CLP Annex VI (ECHA)
1 classifications
| Hazard Class | H-Statements | Pictograms | Signal |
|---|---|---|---|
| Flam. Gas 1; Press. Gas | H220 | GHS02; GHS04 | Danger |
ICSC Chemical Safety
International Chemical Safety Card hazard and exposure summary.
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ILO/WHO International Chemical Safety Cards
1 records
| Field | Value |
|---|---|
| GHS Signal Word | DANGER |
| GHS Hazard Statements | Extremely flammable gas Contains gas under pressure; may explode if heated |
| Short-term Effects | Asphyxiation. See Notes. Exposure to cold gas could cause frostbite. |
| Routes of Exposure | Exposure mainly occurs via inhalation. |
Functional Uses
Industrial and product-use categories associated with this substance.
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EPA CPDat
2 records
AntioxidantAdhesion/cohesion promoter
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
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EPA CPDat
4 records
| List | Keyword | Source |
|---|---|---|
| drinking_water; Europe; manufacturing; plastic_additive | Belgaqua | CPCat |
| pharmaceutical | US International Trade Commission | CPCat |
| Indirect additives food contact (10/2018) | FDA | United States Food and Drug Administration (FDA) |
| Canada; pharmaceutical | DrugBank | DrugBank |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 5 of 5 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 7YNJ3PO35Z | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 7YNJ3PO35Z | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 7YNJ3PO35Z | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 7YNJ3PO35Z | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =3298.18 | mg/m3 | LEL | inhalation | Human | ToxValDB_DOE_Protective_Action_Criteria |
Showing 5 of 5 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
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CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Cosmetic Ingredient
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
ChEMBL Phase
Not listed
Adverse Events
9
Bioactivity
0
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
FDA GRAS: FDA has no questions
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What is the NOAEL for Hydrogen?
Hydrogen has 5 NOAEL studies in the database. The lowest reported value is 7YNJ3PO35Z UNII. Source: openFDA substances.
What regulatory lists include Hydrogen?
Hydrogen appears on 4 regulatory/inventory lists including drinking_water; Europe; manufacturing; plastic_additive, pharmaceutical, Indirect additives food contact (10/2018), and 1 more. Source: EPA CPDat.
Is Hydrogen used in cosmetics?
Yes, Hydrogen is also indexed as a cosmetic ingredient under the name Hydrogen. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Hydrogen come from?
Safety data is sourced from ECHA CLP Annex VI, EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ILO/WHO ICSC, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Does Hydrogen have different safety status in cosmetics vs industrial chemicals?
Hydrogen is classified GHS Danger (H220) in the chemicals database but is allowed in EU cosmetics.
Is Hydrogen used outside industrial chemicals?
Hydrogen also appears in cosmetics, pharmaceutical, food safety, cannabis databases.