Moderate Cosmetic Ingredient GHS Classified

Hydrogen

Also known as: Dihydrogen, Hydrogen molecule, Mol. hydrogen, Molecular hydrogen, Orthohydrogen (+13 more)

INCI: HYDROGEN

Hydrogen (CAS 1333-74-0) is a cosmetic cosmetic ingredient functioning as Propellant. EU Regulation 1223/2009 status: permitted; GHS signal word DANGER. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety, pharmaceutical, and food safety data.

View industrial chemical safety profile for CAS 1333-74-0 →

Auto-generated CPSR Part A draft with source citations
Function
Propellant
Safety Rating
MODERATE

Chemistry & Identifiers

Formula
H2
MW
2.016 g/mol
PubChem CID
783
IUPAC Name
molecular hydrogen
InChIKey
UFHFLCQGNIYNRP-UHFFFAOYSA-N

Regulatory Status

EU EU Status permitted
US US Status permitted
US Notes Permitted — no CFR restriction for cosmetic use

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Hydrogen.

Calculate MoS for your specific formulation with the MoS Calculator.

GHS Hazard Classification

Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.

Signal Word
DANGER
Pictograms
FlamFlameCylinderGas
Hazard Statements
Extremely flammable gas Contains gas under pressure; may explode if heated
Short-term Exposure Effects
Asphyxiation. See Notes. Exposure to cold gas could cause frostbite.
Routes of Exposure
Exposure mainly occurs via inhalation.

EU CLP Annex VI Harmonized Classification

Legally binding harmonized classification per Regulation (EC) No 1272/2008 (CLP) Annex VI.

Signal Word
Danger
Pictograms
FlammableCompressed Gas
Hazard Class and Category
Flam. Gas 1; Press. Gas
Hazard Statements
  • H220 Extremely flammable gas

Inserted via ATP: CLP00

PubChem Annotations

Safety and regulatory annotations from PubChem (NCBI) aggregated sources.

Safety (1)
ICSC Safety Card
0001
Source: ILO-WHO International Chemical Safety Cards (ICSCs)
Regulatory (1)
EU Food Improvement
Food additives
Source: EU Food Improvement Agents

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Adhesion/cohesion promoter Antioxidant
Regulatory List Membership (1)
FDA Indirect Food Contact Additives

Expert Verdict

Expert safety assessment and concern-level summary for Hydrogen.

Known Synonyms

Dihydrogen Hydrogen molecule Mol. hydrogen Molecular hydrogen Orthohydrogen Parahydrogen Hydrogen gas Hydrogen element Hydrogen (H2) EINECS 215-605-7 Hydrogen atoms UNII-7YNJ3PO35Z E 949 E-949 E949 H2 Nascent hydrogen Elemental hydrogen

Chemical Function

Antioxidant Adhesion/cohesion promoter

Regulatory Lists

drinking_water; Europe; manufacturing; plastic_additive pharmaceutical Indirect additives food contact (10/2018) Canada; pharmaceutical

Australian Status

AICIS status: listed

Cross-Vertical Safety Context

Same-CAS public records found in pharmaceutical and food safety data.

SOURCE ChEMBL / DrugCentral / FAERS DB_PHARMA count match

Pharmaceutical Data

Same-CAS rows from the pharmaceutical spoke database.

Adverse Event Associations
9
View full pharmaceutical profile →
SOURCE EFSA / FDA GRAS fda_gras_enriched

Food Safety Data

Same-CAS food additive or FDA GRAS records from the core public database.

Food Name
Hydrogen gas
FDA GRAS
FDA has no questions
GRN
520

For use as an ingredient in drinking water, flavored beverages, and soda drinks at a level up to 2.14% by volume.

View full food safety profile →

Frequently Asked Questions

Is Hydrogen safe in cosmetics?

Hydrogen has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.

Is Hydrogen allowed in the EU?

Hydrogen EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Hydrogen do in cosmetics?

Hydrogen functions as: Propellant. It is classified as a cosmetic ingredient in our database. CAS number: 1333-74-0.

Is Hydrogen classified as hazardous under GHS?

Hydrogen carries a GHS signal word of "DANGER". Hazard statements: Extremely flammable gas Contains gas under pressure; may explode if heated. This classification is based on the ILO/WHO International Chemical Safety Card and ECHA C&L inventory data. Note: GHS classification applies to the pure substance — at cosmetic use concentrations, hazard thresholds may not be met.

Is Hydrogen used outside cosmetics?

Hydrogen also appears in industrial chemical safety, pharmaceutical, and food safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

Does Hydrogen have different safety status in cosmetics vs industrial chemicals?

Hydrogen is classified GHS Danger (H220, H280, H281) in the chemicals database but is allowed in EU cosmetics.

Is Hydrogen in Your Products?

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