What is the NOAEL for Prop-2-en-1-yl heptanoate?
Prop-2-en-1-yl heptanoate has 28 NOAEL studies in the database. The lowest reported value is 0.15 mg/kg via oral in Human. Source: WHO/JECFA.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Prop-2-en-1-yl heptanoate
Also known as: Heptanoic acid, 2-propenyl ester, Allyl heptanoate, Heptanoic acid, 2-propen-1-yl ester, Allyl enanthate, Allyl heptoate (+7 more)
CAS 142-19-8
Prop-2-en-1-yl heptanoate (CAS 142-19-8) is a chemical substance. Key regulatory status: REACH registered, 10 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
Cross-Vertical Regulatory Divergence
Prop-2-en-1-yl heptanoate is classified GHS Danger (H301, H302, H312, H311, H315, H319, H373, H400) in the chemicals database but is restricted in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
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NOAEL studies
NOAEL studies
28
SOURCE
Chemical inventory jurisdictions
Regulatory lists
10
SOURCE
EU CLP Annex VI
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
17 fields
Name
Prop-2-en-1-yl heptanoate
CAS Number
142-19-8
Molecular Formula
C10H18O2
InChI Key
SJWKGDGUQTWDRV-UHFFFAOYSA-N
Monoisotopic Mass
170.13068
Synonyms
Heptanoic acid, 2-propenyl esterAllyl heptanoateHeptanoic acid, 2-propen-1-yl esterAllyl enanthateAllyl heptoateAllyl heptylateEINECS 205-527-1FEMA No. 2031NSC 209692-Propenyl heptanoateAllylester kyseliny enanthoveUNII-AU4CYG9V68
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
60 records
FragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
10 records
| List | Keyword | Source |
|---|---|---|
| air; detected; emissions; Europe; Vehicle - car interior | Danish Environmental Protection Agency | Danish EPA |
| air; detected; emissions; Europe; Vehicle - car interior | Danish Environmental Protection Agency | Danish EPA |
| detected; Europe; Vehicle - car interior | Danish Environmental Protection Agency | Danish EPA |
| air; detected; emissions; Personal care | Elsevier | CPCat |
| air; Cleaning products and household care - air freshener; detected; emissions | Elsevier | CPCat |
| IFRA Transparency | IFRA | IFRA |
| Europe | European Commission | Fl@vis |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| consumer_product | P&G | Proctor & Gamble |
| Europe; Personal care; restricted | European Commission | CosIng |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 28 of 28 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| <=0.15 | mg/kg | ADI | oral | Human | WHO/JECFA |
| =2.97 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB GESTIS DNEL |
| AU4CYG9V68 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 0 | % | Incidence of positive responses | Dermal | Human | NTP ICE skin sensitization |
| 1350 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP ICE skin sensitization |
| 2592 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP ICE skin sensitization |
| 25 | mg/kg bw/day | LOAEL | oral | dog | COSMOS DB |
| 49.6 | mg/kg bw/day | LOAEL | oral | rat | COSMOS DB |
| 100 | mg/kg bw/day | LOAEL | oral | rat | COSMOS DB |
| 5 | mg/kg bw/day | NOAEL | oral | rat | COSMOS DB |
| 25 | mg/kg bw/day | NOAEL | oral | dog | COSMOS DB |
| 30 | mg/kg bw/day | NOAEL | oral | rat | COSMOS DB |
| 49.6 | mg/kg bw/day | NOAEL | oral | rat | COSMOS DB |
| 75 | mg/kg bw/day | NOAEL | oral | dog | COSMOS DB |
| 100 | mg/kg bw/day | NOAEL | oral | rat | COSMOS DB |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP ICE skin sensitization |
| 94.3 | % | Viability | Dermal | - | NTP ICE skin irritation |
| 97.01 | % | Viability | Dermal | - | NTP ICE skin irritation |
| 98.9 | % | Viability | Dermal | - | NTP ICE skin irritation |
| 99.53 | % | Viability | Dermal | - | NTP ICE skin irritation |
| 101.1 | % | Viability | Dermal | - | NTP ICE skin irritation |
| 101.3 | % | Viability | Dermal | - | NTP ICE skin irritation |
| 102.1 | % | Viability | Dermal | - | NTP ICE skin irritation |
| 102.2 | % | Viability | Dermal | - | NTP ICE skin irritation |
| 103.7 | % | Viability | Dermal | - | NTP ICE skin irritation |
| 105.4 | % | Viability | Dermal | - | NTP ICE skin irritation |
| 105.9 | % | Viability | Dermal | - | NTP ICE skin irritation |
| 109.4 | % | Viability | Dermal | - | NTP ICE skin irritation |
Showing 28 of 28 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Allyl heptanoate | 205-527-1 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
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AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
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CosIng / Ingredients DB
EU Status
restricted
Max
-
Category
Fragrance
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
ChEMBL / DailyMed
ALLYL HEPTANOATE
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Prop-2-en-1-yl heptanoate?
Prop-2-en-1-yl heptanoate appears on 9 regulatory/inventory lists including air; detected; emissions; Europe; Vehicle - car interior, detected; Europe; Vehicle - car interior, air; detected; emissions; Personal care, and 6 more. Source: EPA CPDat.
Is Prop-2-en-1-yl heptanoate used in cosmetics?
Yes, Prop-2-en-1-yl heptanoate is also indexed as a cosmetic ingredient under the name Allyl Heptanoate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Prop-2-en-1-yl heptanoate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Does Prop-2-en-1-yl heptanoate have different safety status in cosmetics vs industrial chemicals?
Prop-2-en-1-yl heptanoate is classified GHS Danger (H301, H302, H312, H311, H315, H319, H373, H400) in the chemicals database but is restricted in EU cosmetics.
Is Prop-2-en-1-yl heptanoate used outside industrial chemicals?
Prop-2-en-1-yl heptanoate also appears in cosmetics, pharmaceutical, cannabis databases.