What is the NOAEL for Dyphylline?
Dyphylline has 4 NOAEL studies in the database. The lowest reported value is 263T0E9RR9 UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Dyphylline
Also known as: 5-26-14-00070, BRN 0284563, Dihydroxypropyl theophylline, 7-(2,3-Dioxypropyl)theophylline, Diprofilline (+15 more)
CAS 479-18-5
Dyphylline (CAS 479-18-5) is a chemical substance. Key regulatory status: 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat.
Cross-Vertical Regulatory Divergence
Dyphylline is classified GHS Danger (H302, H370, H372, H332) in the chemicals database but is allowed in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
3
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
26 fields
Name
Dyphylline
CAS Number
479-18-5
DTXSID
DTXSID6022975
Molecular Formula
C10H14N4O4
InChI Key
KSCFJBIXMNOVSH-UHFFFAOYSA-N
Monoisotopic Mass
254.101505
Synonyms
5-26-14-00070BRN 0284563Dihydroxypropyl theophylline7-(2,3-Dioxypropyl)theophyllineDiprofillineDipropyllineDroxineEINECS 207-526-1GlyphyllinumLiactemin1H-Purine-2,6-dione, 7-(2,3-dihydroxypropyl)-3,7-dihydro-1,3-dimethylDiprofillina
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
1 records
Softener and conditioner
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
3 records
| List | Keyword | Source |
|---|---|---|
| pharmaceutical | US International Trade Commission | CPCat |
| active_ingredient; animal_products; Europe; pharmaceutical; residue | EU | CPCat |
| Canada; pharmaceutical | DrugBank | DrugBank |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 263T0E9RR9 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 263T0E9RR9 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 263T0E9RR9 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 263T0E9RR9 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Cosmetic Ingredient
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
DYPHYLLINE
ChEMBL Phase
4
Adverse Events
35
Bioactivity
5
Frequently Asked Questions
What regulatory lists include Dyphylline?
Dyphylline appears on 3 regulatory/inventory lists including pharmaceutical, active_ingredient; animal_products; Europe; pharmaceutical; residue, Canada; pharmaceutical. Source: EPA CPDat.
Is Dyphylline used in cosmetics?
Yes, Dyphylline is also indexed as a cosmetic ingredient under the name Dyphylline. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Dyphylline come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Does Dyphylline have different safety status in cosmetics vs industrial chemicals?
Dyphylline is classified GHS Danger (H302, H370, H372, H332) in the chemicals database but is allowed in EU cosmetics.
Is Dyphylline used outside industrial chemicals?
Dyphylline also appears in cosmetics, pharmaceutical databases.