What is the NOAEL for Nerolidol?
Nerolidol has 8 NOAEL studies in the database. The lowest reported value is 10 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Nerolidol
Also known as: 3-hydroxy-3,7,11-trimethyl-1,6,10-dodecatriene, 3-01-00-02042, BRN 1724135, EINECS 230-597-5, FEMA No. 2772 (+3 more)
CAS 7212-44-4
Nerolidol (CAS 7212-44-4) is a chemical substance. Key regulatory status: REACH registered, 18 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
8
SOURCE
chemical inventory jurisdictions
Regulatory lists
18
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
14 fields
Name
Nerolidol
CAS Number
7212-44-4
DTXSID
DTXSID3022247
Molecular Formula
C15H26O
InChI Key
FQTLCLSUCSAZDY-UHFFFAOYSA-N
Monoisotopic Mass
222.198365
Synonyms
3-hydroxy-3,7,11-trimethyl-1,6,10-dodecatriene3-01-00-02042BRN 1724135EINECS 230-597-5FEMA No. 2772Methylvinylhomogeranyl carbinolEPA Pesticide Chemical Code 128910UNII-QR6IP857S6
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
37 records
FragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
18 records
| List | Keyword | Source |
|---|---|---|
| active_ingredient; Europe; Pesticides | European Commission | CPCat |
| pharmaceutical | US International Trade Commission | CPCat |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | California Department of Pesticide Regulation | State of California |
| active_ingredient; agricultural; Pesticides | USDA | United States Department of Agriculture (USDA) |
| active_ingredient; agricultural; Pesticides | USDA | United States Department of Agriculture (USDA) |
| active_ingredient; agricultural; Pesticides | USDA | United States Department of Agriculture (USDA) |
| active_ingredient; agricultural; Pesticides | USDA | United States Department of Agriculture (USDA) |
| Europe | European Commission | Fl@vis |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| IFRA Transparency | IFRA | IFRA |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 8 of 8 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =10 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| QR6IP857S6 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| QR6IP857S6 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| QR6IP857S6 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| QR6IP857S6 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| >5000 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| =500 | mg/kg bw/day | LOEL | oral | House Mouse | ToxValDB_ECOTOX |
| - | unitless | Model Score | - | - | NTP_ICE_endocrine |
Showing 8 of 8 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 3,7,11-trimethyldodeca-1,6,10-trien-3-ol,mixed isomers | 230-597-5 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
terpene
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
ADI: No safety concern at current levels of intake when used as a flavouring agent mg/kg bw
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Nerolidol?
Nerolidol appears on 7 regulatory/inventory lists including active_ingredient; Europe; Pesticides, pharmaceutical, active_ingredient; Pesticides, and 4 more. Source: EPA CPDat.
Is Nerolidol used in cosmetics?
Yes, Nerolidol is also indexed as a cosmetic ingredient under the name Nerolidol. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Nerolidol come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is Nerolidol used outside industrial chemicals?
Nerolidol also appears in cosmetics, food safety, cannabis databases.