What is the GHS hazard classification for Cellulase?
Cellulase (CAS 9012-54-8) is classified under EU CLP Annex VI as Resp. Sens. 1 with signal word Danger. Hazard statements: H334. Source: EU CLP Annex VI (ECHA).
Danger
GHS08
NOAEL Data
REACH Registered
Cosmetic Ingredient
Cellulase
Also known as: EINECS 232-734-4
CAS 9012-54-8
Cellulase (CAS 9012-54-8) is a chemical substance with GHS signal word Danger; key hazard signal: H334. Key regulatory status: REACH registered, 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from ECHA CLP, EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
Cross-Vertical Regulatory Divergence
Cellulase is classified GHS Danger (H334) in the chemicals database but is allowed in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: eu_clp_annex_vi.signal_word/hazard_statement_code
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noael studies public
NOAEL studies
7
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chemical inventory jurisdictions
Regulatory lists
3
SOURCE
eu clp annex vi
GHS signal
Danger
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
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DSSTox identifiers
4 fields
Name
Cellulase
CAS Number
9012-54-8
DTXSID
DTXSID2049638
Synonyms
EINECS 232-734-4
GHS / CLP Classification
EU harmonized hazard classification, hazard statements, pictograms, and signal word.
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EU CLP Annex VI (ECHA)
1 classifications
| Hazard Class | H-Statements | Pictograms | Signal |
|---|---|---|---|
| Resp. Sens. 1 | H334 | GHS08 | Danger |
Functional Uses
Industrial and product-use categories associated with this substance.
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EPA CPDat
60 records
Cleaning agentChemical reaction regulatorViscosity modifierPharmaceuticalAnti-stain agent
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
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EPA CPDat
3 records
| List | Keyword | Source |
|---|---|---|
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
| SCIL (9/2019) | USEPA | Safer Chemical Ingredients List |
| fracking; water | NY Department of Conservation | CPCat |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 7 of 7 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 7Q170212NX | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 7Q170212NX | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 7Q170212NX | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 7Q170212NX | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| >=1000 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| >=1013.3 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| >1000 | mg/kg bw/day | NOEL | oral | Rat | ToxValDB_ECHA_IUCLID |
Showing 7 of 7 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
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ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Cellulase | 232-734-4 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
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AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
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CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Skin Conditioning
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
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EFSA / FDA GRAS
1 records
FDA GRAS: FDA has no questions
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What is the NOAEL for Cellulase?
Cellulase has 7 NOAEL studies in the database. The lowest reported value is 7Q170212NX UNII. Source: openFDA substances.
What regulatory lists include Cellulase?
Cellulase appears on 3 regulatory/inventory lists including inert_ingredient; non_food_use; Pesticides, SCIL (9/2019), fracking; water. Source: EPA CPDat.
Is Cellulase used in cosmetics?
Yes, Cellulase is also indexed as a cosmetic ingredient under the name Cellulase. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Cellulase come from?
Safety data is sourced from ECHA CLP Annex VI, EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Does Cellulase have different safety status in cosmetics vs industrial chemicals?
Cellulase is classified GHS Danger (H334) in the chemicals database but is allowed in EU cosmetics.
Is Cellulase used outside industrial chemicals?
Cellulase also appears in cosmetics, food safety, cannabis databases.