Food Safety Substance
Ethylenediamine
Ethylenediamine is a food additive with no EU additive status row found in the EU, FDA has no questions in the US, and data from 8 regulatory sources.
CAS 107-15-3
Indexable evidence set
FDA
FDA has no questions
ADI / TDI
JECFA ADI 0-2.5 mg/kg bw
Codex
0 row(s)
SOURCE
D1 identity resolution
e number aliases | Food Additives | dsstox identifiers | 8 matched regulatory source group(s)
Substance Identity
Resolved identifiers used to render this food-safety record.
Substance name
Ethylenediamine
CAS
107-15-3
DTXSID
DTXSID5021881
PubChem CID
3301
Evidence tier
Indexable evidence set (12)
SOURCE
EU Commission
FDA | Health Canada | Codex Alimentarius
Multi-Jurisdiction Comparison
Side-by-side status rows for the same resolved substance across public food regulators.
| Jurisdiction | Authority | Status | Evidence |
|---|---|---|---|
| United States | FDA | FDA has no questions | GRAS notice |
| Canada | Health Canada | Listed | Sequestering agent |
SOURCE
FDA
FDA GRAS
FDA GRAS Status
US FDA GRAS notice evidence from enriched and notice tables.
| Jurisdiction | GRN | Substance | FDA response | Intended use | Basis | Notifier |
|---|---|---|---|---|---|---|
| United States | 363 | Calcium disodium ethylenediaminetetraacetic acid (EDTA) and disodium EDTA | FDA has no questions | Use alone or together as color, flavor, and/or texture retention agents in packaged cooked sweet corn products with or without sauce, including mixed vegetable and similar... | Scientific procedures | Del Monte Foods |
| United States | 573 | Calcium disodium ethylenediaminetetraacetate (EDTA) | FDA has no questions | For use in soft drinks, coffees and teas, flavored coffees and teas, concentrated flavor enhancer drops, energy drinks, enhanced water beverages, flavored milk beverages, fruit... | Scientific procedures | Exponent Inc. |
| United States | 1044 | Calcium disodium ethylenediaminetetraacetic acid | At the notifier's request, FDA ceased to evaluate this notice | Intended for use as a color retention agent for canned abalone in brine. The concentration of calcium disodium EDTA in the canned abalone is up to 250 mg/kg. | Scientific procedures | Jade Tiger Abalone |
| United States | 363 | Calcium disodium ethylenediaminetetraacetic acid (EDTA) and disodium EDTA | FDA has no questions | Use alone or together as color, flavor, and/or texture retention agents in packaged cooked sweet corn products with or without sauce, including mixed vegetable and similar... | Scientific procedures | Del Monte Foods |
| United States | 573 | Calcium disodium ethylenediaminetetraacetate (EDTA) | FDA has no questions | For use in soft drinks, coffees and teas, flavored coffees and teas, concentrated flavor enhancer drops, energy drinks, enhanced water beverages, flavored milk beverages, fruit... | Scientific procedures | Exponent Inc. |
| United States | 1044 | Calcium disodium ethylenediaminetetraacetic acid | At the notifier's request, FDA ceased to evaluate this notice (in PDF) | Intended for use as a color retention agent for canned abalone in brine. The concentration of calcium disodium EDTA in the canned abalone is up to 250 mg/kg. | Scientific procedures | Jade Tiger Abalone |
SOURCE
Health Canada
Health Canada Status
Health Canada food-additive permissions by functional class and food scope.
| Jurisdiction | Class | Permitted foods | Maximum level | List |
|---|---|---|---|---|
| Canada | Sequestering agent | (a) Beans; Beans with pork | (a) 365 ppm, calculated as the anhydrous form | List of Permitted Sequestering Agents |
| Canada | Sequestering agent | (a) Aqueous suspensions of colour lake preparations for use in coating confectionery tablets | (a) 1% of the colour preparation | List of Permitted Sequestering Agents |
SOURCE
EU Commission
EU Food Contact Materials
EU FCM Substances
EU food-contact material rows and migration-limit fields.
| Jurisdiction | FCM no. | Ref no. | Substance | Use | SML | Regulation |
|---|---|---|---|---|---|---|
| European Union | 111 | 53600 | ethylenediaminetetraacetic acid | additive/PPA | - | Regulation (EU) No 10/2011, Annex I |
| European Union | 204 | 25180 | N,N,N′,N′-tetrakis(2-hydroxypropyl)ethylenediamine | additive/PPA, monomer/macromolecule | - | Regulation (EU) No 10/2011, Annex I |
| European Union | 226 | 15272 | ethylenediamine | monomer/macromolecule | 12 mg/kg | Regulation (EU) No 10/2011, Annex I |
| European Union | 305 | 15274 | hexamethylenediamine | monomer/macromolecule | 2,4 mg/kg | Regulation (EU) No 10/2011, Annex I |
| European Union | 701 | 40160 | N,N′-bis(2,2,6,6-tetramethyl-4-piperidyl)hexamethylenediamine-1,2-dibromoethane, copolymer | additive/PPA | 2,4 mg/kg | Regulation (EU) No 10/2011, Annex I |
| European Union | 767 | 38510 | 1,2-bis(3-aminopropyl)ethylenediamine, polymer with N-butyl-2,2,6,6-tetramethyl-4-piperidinamine and 2,4,6-trichloro-1,3,5-triazine | additive/PPA | 5 mg/kg | Regulation (EU) No 10/2011, Annex I |
| European Union | 795 | 40155 | N,N′-bis(2,2,6,6-tetramethyl-4-piperidyl)-N,N′-diformylhexamethylenediamine | additive/PPA | 0,05 mg/kg | Regulation (EU) No 10/2011, Annex I |
SOURCE
JECFA
JECFA ADI
JECFA ADI Values
JECFA ADI records and evaluation years.
| Jurisdiction | Chemical name | JECFA no. | CAS | ADI | ADI upper | Function | Evaluation year |
|---|---|---|---|---|---|---|---|
| JECFA | DISODIUM ETHYLENEDIAMINETETRAACETATE | - | 139-33-3 | 0-2.5 mg/kg bw | 2.5 | ANTIOXIDANT_SYNERGIST, PRESERVATIVE, SEQUESTRANT, SYNERGIST | 1973 |
| JECFA | SODIUM IRON (III) ETHYLENEDIAMINETETRAACETATE, TRIHYDRATE | - | 15708-41-5 | 0-1.9 mg/kg bw (as EDTA) | 1.9 | NUTRIENT_SUPPLEMENT | 2007 |
| JECFA | CALCIUM DISODIUM ETHYLENEDIAMINETETRAACETATE | - | 662-33-9 | 0-2.5 mg/kg bw | 2.5 | PRESERVATIVE, SEQUESTRANT | 1973 |
| JECFA | DIETHYLENEDIAMINE | - | - | no_data | - | - | 2008 |
SOURCE
ingredients
ghs classifications
Cross-Reference to Cosmetics / Chemicals / Pharma
Same-CAS public rows from adjacent Roots verticals where available.
SOURCE
Cross-vertical comparison
ingredients | ghs classifications
Cross-Vertical Regulatory Divergence
This substance has different regulatory treatment across food, cosmetics, and industrial use.
SOURCE
FAQPage JSON-LD
public food renderer rows
Frequently Asked Questions
Food-use, safety, ADI, and cross-vertical answers mirrored into FAQPage JSON-LD.
What is Ethylenediamine used for in food?
Ethylenediamine appears in food-use rows as: TRACER; Sequestering agent.
Is Ethylenediamine safe?
This page does not assign a standalone safety verdict; it renders public regulatory evidence. ADI/reference value: JECFA ADI 0-2.5 mg/kg bw. US/FDA evidence: FDA has no questions.
What is the ADI for Ethylenediamine?
Ethylenediamine has this ADI/reference value in the food-safety tables: JECFA ADI 0-2.5 mg/kg bw. Source: JECFA 1973.
Is Ethylenediamine also used in cosmetics?
Ethylenediamine has a same-CAS cosmetics cross-reference: Ethylenediamine ⚠️, EU status prohibited.