Ethylenediamine ⚠️

Strong sensitizer (Skin Sens. 1A) included in dermatological patch test baseline series with corrosive effects to eyes (H318) and acute toxicity concerns; if present as residual monomer in ethylenediamine-based copolymers, must be controlled below 10 ppm or NESIL-derived safe threshold and is not recommended for leave-on cosmetics unless present only as trace impurity. The EU classifies Ethylenediamine ⚠️ as "prohibited". Safety rating: POOR. 10 toxicological study endpoint(s) are available in our database.

Ethylenediamine ⚠️ EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

Ethylenediamine ⚠️ functions as: Chelating agent, pH adjuster, intermediate (rarely used standalone in finished cosmetics). It is classified as a cosmetic ingredient in our database. CAS number: 107-15-3.

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

The NOAEL (No Observed Adverse Effect Level) for Ethylenediamine ⚠️ is 250 mg/kg bw/day based on a Short Term Toxicity study via oral route in rat. A total of 10 study endpoints are available. Source: COSMOS_DB.

Ethylenediamine ⚠️ carries a GHS signal word of "DANGER". Hazard statements: Flammable liquid and vapour Harmful if swallowed or in contact with skin Causes severe skin burns and eye damage May cause an allergic skin reaction May cause allergy or asthma symptoms or breathing difficulties if inhaled. This classification is based on the ILO/WHO International Chemical Safety Card and ECHA C&L inventory data. Note: GHS classification applies to the pure substance — at cosmetic use concentrations, hazard thresholds may not be met.