Food Safety Substance
Piperine
Piperine is a food additive with Not novel food (from black pepper) in the EU, At the notifier's request, FDA ceased to evaluate this notice in the US, and data from 6 regulatory sources.
Substance Identity
Resolved identifiers used to render this food-safety record.
Multi-Jurisdiction Comparison
Side-by-side status rows for the same resolved substance across public food regulators.
| Jurisdiction | Authority | Status | Evidence |
|---|---|---|---|
| European Union | EU Commission | Not novel food (from black pepper) | - |
| United States | FDA | At the notifier's request, FDA ceased to evaluate this notice | GRAS notice |
FDA GRAS Status
US FDA GRAS notice evidence from enriched and notice tables.
| Jurisdiction | GRN | Substance | FDA response | Intended use | Basis | Notifier |
|---|---|---|---|---|---|---|
| United States | 474 | Piperine derived from the fruits of Piper nigrum L (black pepper) or P. longum (long pepper) | At the notifier's request, FDA ceased to evaluate this notice | As a flavoring agent in food | Scientific procedures | Sabinsa Corporation |
| United States | 474 | Piperine derived from the fruits of <i>Piper nigrum</i> L (black pepper) or <i>P. longum</i> (long pepper) | At the notifier's request, FDA ceased to evaluate this notice | As a flavoring agent in food | Scientific procedures | Sabinsa Corporation |
JECFA ADI Values
JECFA ADI records and evaluation years.
| Jurisdiction | Chemical name | JECFA no. | CAS | ADI | ADI upper | Function | Evaluation year |
|---|---|---|---|---|---|---|---|
| JECFA | PIPERINE | 1600 | - | No safety concern at current levels of intake when used as a flavouring agent | - | FLAVOURING_AGENT | 2005 |
Cross-Reference to Cosmetics / Chemicals / Pharma
Same-CAS public rows from adjacent Roots verticals where available.
Cross-Vertical Regulatory Divergence
This substance has different regulatory treatment across food, cosmetics, and industrial use.
Frequently Asked Questions
Food-use, safety, ADI, and cross-vertical answers mirrored into FAQPage JSON-LD.
What is Piperine used for in food?
Piperine appears in food-use rows as: botanical.
Is Piperine safe?
This page does not assign a standalone safety verdict; it renders public regulatory evidence. ADI/reference value: ADI No safety concern at current levels of intake when used as a flavouring agent mg/kg bw. EU status evidence: Not novel food (from black pepper). US/FDA evidence: At the notifier's request, FDA ceased to evaluate this notice.
What is the ADI for Piperine?
Piperine has this ADI/reference value in the food-safety tables: ADI No safety concern at current levels of intake when used as a flavouring agent mg/kg bw. Source: WHO JECFA.
Is Piperine also used in cosmetics?
Piperine has a same-CAS cosmetics cross-reference: Piperine, EU status permitted.