Good Cosmetic Ingredient NOAEL Data

2-Tert-Butylcyclohexyl Ethyl Carbonate

INCI: 2-TERT-BUTYLCYCLOHEXYL ETHYL CARBONATE

CAS Number
67801-64-3
Function
Perfuming (fragrance)
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” listed on TSCA inventory; no specific FDA cosmetic restriction

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

2 study endpoints found for 2-Tert-Butylcyclohexyl Ethyl Carbonate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL >=500 mg/kg bw/day oral rat oral REACH
NOAEL >500 mg/kg bw/day oral - oral REACH

Expert Verdict

Aquatic Chronic 3 (H412) โ€” harmful to aquatic life with long-lasting effects; spicy-woody-floral odor

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Concern Level: Moderate

Regulatory Flags

fragrance-component ifra_fragrance

Frequently Asked Questions

Is 2-Tert-Butylcyclohexyl Ethyl Carbonate safe in cosmetics?

Aquatic Chronic 3 (H412) โ€” harmful to aquatic life with long-lasting effects; spicy-woody-floral odor The EU classifies 2-Tert-Butylcyclohexyl Ethyl Carbonate as "permitted". Safety rating: GOOD. 2 toxicological study endpoint(s) are available in our database.

Is 2-Tert-Butylcyclohexyl Ethyl Carbonate allowed in the EU?

2-Tert-Butylcyclohexyl Ethyl Carbonate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does 2-Tert-Butylcyclohexyl Ethyl Carbonate do in cosmetics?

2-Tert-Butylcyclohexyl Ethyl Carbonate functions as: Perfuming (fragrance). It is classified as a cosmetic ingredient in our database. CAS number: 67801-64-3.

What is the Margin of Safety for 2-Tert-Butylcyclohexyl Ethyl Carbonate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for 2-Tert-Butylcyclohexyl Ethyl Carbonate?

The NOAEL (No Observed Adverse Effect Level) for 2-Tert-Butylcyclohexyl Ethyl Carbonate is >=500 mg/kg bw/day based on a oral study via oral route in rat. A total of 2 study endpoints are available. Source: REACH.

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