Excellent Cosmetic Ingredient NOAEL Data

2,6-Dimethyl-7-octen-2-ol (Dihydromyrcenol)

INCI: 2,6-DIMETHYL-7-OCTEN-2-OL

CAS Number
18479-58-8
Function
Fragrance (perfuming), masking
Safety Rating
EXCELLENT

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not individually regulated; fragrance exemption applies. FEMA GRAS listed for flavor use

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

4 study endpoints found for 2,6-Dimethyl-7-octen-2-ol (Dihydromyrcenol). NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOEL 50 mg/kg bw/day oral rat oral REACH
NOAEL 1000 mg/kg bw/day oral rat oral REACH
NOAEL 500 mg/kg bw/day oral - oral REACH
NOAEL 1000 mg/kg bw/day oral - oral REACH

Expert Verdict

Synthetic origin . Very high-volume ingredient - ensure supplier provides batch-specific purity and impurity profiling. No significant regulatory or safety flags

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Concern Level: None

Regulatory Flags

fragrance-component epa_safer_alternative ifra_fragrance

Frequently Asked Questions

Is 2,6-Dimethyl-7-octen-2-ol (Dihydromyrcenol) safe in cosmetics?

Synthetic origin . Very high-volume ingredient - ensure supplier provides batch-specific purity and impurity profiling. No significant regulatory or safety flags The EU classifies 2,6-Dimethyl-7-octen-2-ol (Dihydromyrcenol) as "permitted". Safety rating: EXCELLENT. 4 toxicological study endpoint(s) are available in our database.

Is 2,6-Dimethyl-7-octen-2-ol (Dihydromyrcenol) allowed in the EU?

2,6-Dimethyl-7-octen-2-ol (Dihydromyrcenol) EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does 2,6-Dimethyl-7-octen-2-ol (Dihydromyrcenol) do in cosmetics?

2,6-Dimethyl-7-octen-2-ol (Dihydromyrcenol) functions as: Fragrance (perfuming), masking. It is classified as a cosmetic ingredient in our database. CAS number: 18479-58-8.

What is the Margin of Safety for 2,6-Dimethyl-7-octen-2-ol (Dihydromyrcenol)?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for 2,6-Dimethyl-7-octen-2-ol (Dihydromyrcenol)?

The NOAEL (No Observed Adverse Effect Level) for 2,6-Dimethyl-7-octen-2-ol (Dihydromyrcenol) is 50 mg/kg bw/day based on a oral study via oral route in rat. A total of 4 study endpoints are available. Source: REACH.

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