Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
1 study endpoint found for Acetoin. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 1320 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
Expert Verdict
Naturally occurring in dairy, fruits, and fermented foods with no significant safety concerns. Environmental PEC/PNEC also cleared.
Regulatory Flags
Frequently Asked Questions
Is Acetoin safe in cosmetics?
Naturally occurring in dairy, fruits, and fermented foods with no significant safety concerns. Environmental PEC/PNEC also cleared. The EU classifies Acetoin as "permitted". Safety rating: EXCELLENT. 1 toxicological study endpoint(s) are available in our database.
Is Acetoin allowed in the EU?
Acetoin EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Acetoin do in cosmetics?
Acetoin functions as: Skin conditioning, fragrance. It is classified as a cosmetic ingredient in our database. CAS number: 513-86-0.
What is the Margin of Safety for Acetoin?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Acetoin?
The NOAEL (No Observed Adverse Effect Level) for Acetoin is 1320 mg/kg bw/day based on a Subchronic study via oral route in rat. Source: COSMOS_DB.
Compliance Tools
Check Acetoin compliance across multiple jurisdictions:
Related Ingredients
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