2,6-Dimethyl-p-phenylenediamine

INCI: 2,6-DIMETHYL-P-PHENYLENEDIAMINE

CAS Number
6738-23-4 (2,6-dimethyl-1,4-benzenediamine)
Function
Hair dyeing (oxidative hair colorant precursor)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status restricted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Covered under coal-tar hair dye exemption (FD\&C Act ยง601(a)); requires caution statement and patch test directions on labeling

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
high
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Oxidative hair dye precursor - requires mixing with Hโ‚‚Oโ‚‚ developer. Cross-reactivity with PPD sensitized individuals possible. Patch testing mandatory per EU labeling requirements. Not permitted for eyelash/eyebrow dyeing . Must verify current Annex III entry number and maximum permitted concentration

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Concern Level: Moderate

Regulatory Flags

potential-allergen colorant

Frequently Asked Questions

Is 2,6-Dimethyl-p-phenylenediamine safe in cosmetics?

Oxidative hair dye precursor - requires mixing with Hโ‚‚Oโ‚‚ developer. Cross-reactivity with PPD sensitized individuals possible. Patch testing mandatory per EU labeling requirements. Not permitted for eyelash/eyebrow dyeing . Must verify current Annex III entry number and maximum permitted concentration The EU classifies 2,6-Dimethyl-p-phenylenediamine as "restricted". Safety rating: MODERATE.

Is 2,6-Dimethyl-p-phenylenediamine allowed in the EU?

2,6-Dimethyl-p-phenylenediamine EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does 2,6-Dimethyl-p-phenylenediamine do in cosmetics?

2,6-Dimethyl-p-phenylenediamine functions as: Hair dyeing (oxidative hair colorant precursor). It is classified as a cosmetic ingredient in our database. CAS number: 6738-23-4 (2,6-dimethyl-1,4-benzenediamine).

What is the Margin of Safety for 2,6-Dimethyl-p-phenylenediamine?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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