Good Cosmetic Ingredient NOAEL Data

3-Isopentenol

INCI: 3-ISOPENTENOL

CAS Number
763-32-6
Function
Fragrance ingredient, solvent
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not specifically restricted by FDA; FEMA GRAS status for flavor use

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

2 study endpoints found for 3-Isopentenol. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
LOAEL 50 mg/kg bw/day oral rat oral REACH
NOAEL 200 mg/kg bw/day oral rat oral REACH

Expert Verdict

Unsaturated alcohol with potential for autoxidation if improperly stored; should be used within IFRA guidelines

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Concern Level: Low

Regulatory Flags

fragrance-component ifra_fragrance

Frequently Asked Questions

Is 3-Isopentenol safe in cosmetics?

Unsaturated alcohol with potential for autoxidation if improperly stored; should be used within IFRA guidelines The EU classifies 3-Isopentenol as "permitted". Safety rating: GOOD. 2 toxicological study endpoint(s) are available in our database.

Is 3-Isopentenol allowed in the EU?

3-Isopentenol EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does 3-Isopentenol do in cosmetics?

3-Isopentenol functions as: Fragrance ingredient, solvent. It is classified as a cosmetic ingredient in our database. CAS number: 763-32-6.

What is the Margin of Safety for 3-Isopentenol?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for 3-Isopentenol?

The NOAEL (No Observed Adverse Effect Level) for 3-Isopentenol is 50 mg/kg bw/day based on a oral study via oral route in rat. A total of 2 study endpoints are available. Source: REACH.

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