Good Cosmetic Ingredient NOAEL Data

4-Methyl-3-Decen-5-Ol

INCI: 4-METHYL-3-DECEN-5-OL

CAS Number

81782-77-6

Function

Fragrance (perfuming); also known as Undecavertol

Safety Rating

GOOD

Regulatory Status

🇪🇺 EU Status permitted

🇺🇸 US Status permitted

US Notes Not specifically regulated; IFRA-managed fragrance ingredient

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)

adequate

Dermal Absorption

low

Sensitization

low

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

4 study endpoints found for 4-Methyl-3-Decen-5-Ol. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint	Value	Route	Species	Study Type	Source
NOEL	10000 ppm	oral	rat	oral	REACH
NOEL	10000 ppm	oral	rat	oral	REACH
NOEL	1000 ppm	oral	rat	oral	REACH
NOEL	1000 ppm	oral	rat	oral	REACH

Expert Verdict

Positive for cytotoxicity in BlueScreen assay (>80% relative cell density reduction), but no genotoxic concern at fragrance use levels

⚠️

Concern Level: Low

Regulatory Flags

fragrance-component epa_safer_alternative ifra_fragrance

Frequently Asked Questions

Is 4-Methyl-3-Decen-5-Ol safe in cosmetics?

Positive for cytotoxicity in BlueScreen assay (>80% relative cell density reduction), but no genotoxic concern at fragrance use levels The EU classifies 4-Methyl-3-Decen-5-Ol as "permitted". Safety rating: GOOD. 4 toxicological study endpoint(s) are available in our database.

Is 4-Methyl-3-Decen-5-Ol allowed in the EU?

4-Methyl-3-Decen-5-Ol EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does 4-Methyl-3-Decen-5-Ol do in cosmetics?

4-Methyl-3-Decen-5-Ol functions as: Fragrance (perfuming); also known as Undecavertol. It is classified as a cosmetic ingredient in our database. CAS number: 81782-77-6.

What is the Margin of Safety for 4-Methyl-3-Decen-5-Ol?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for 4-Methyl-3-Decen-5-Ol?

The NOAEL (No Observed Adverse Effect Level) for 4-Methyl-3-Decen-5-Ol is 10000 ppm based on a oral study via oral route in rat. A total of 4 study endpoints are available. Source: REACH.

Compliance Tools

Check 4-Methyl-3-Decen-5-Ol compliance across multiple jurisdictions:

🔬

Ingredient Decoder

Paste a full ingredient list for instant analysis

🌸

82 Allergen Checker

Check for EU declarable fragrance allergens

🧪

Substance Compliance

Check compliance across 55 jurisdictions

🧮

MoS Calculator

Calculate Margin of Safety using SCCS methodology

⚗️

Heavy Metal Limits

Compare limits across jurisdictions

Related Ingredients

Dibenzyl Ether

Moderate

trans-Methylbutenyl Tiglate

Excellent

Cyclohexylethyl Crotonate

Moderate

Helichrysum Italicum Flower Oil

Moderate

3-Methyl-4-(3,5,6-Trimethyl-3-Cyclohexenyl)-3-Buten-2-One

Good

Browse all 30,000+ ingredients →

📱

Is 4-Methyl-3-Decen-5-Ol in Your Products?

Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free →

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for 4-Methyl-3-Decen-5-Ol in your formulation.

Ingredient Decoder MoS Calculator